ID  Q6CWX4;
PN  Dynein light chain 1, cytoplasmic;
GN  DYN2;
OS  284590;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0185;
SL  Comments: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q02647}. Nucleus, nuclear pore complex {ECO:0000250|UniProtKB:Q02647}.
DR  UNIPROT: Q6CWX4;
DR  Pfam: PF01221;
DR  PROSITE: PS01239;
DE  Function: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity). Also a component of the nuclear pore complex (By similarity). {ECO:0000250, ECO:0000250|UniProtKB:Q02647}.
DE  Reference Proteome: Yes;
GO  GO:0005868;
GO  GO:0005881;
GO  GO:0005643;
GO  GO:1990429;
GO  GO:0005777;
GO  GO:0008574;
GO  GO:0044877;
GO  GO:0040001;
GO  GO:0051028;
GO  GO:0030473;
GO  GO:0051292;
GO  GO:0015031;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MSKPVLKASDITDELRDEIFELSSNATANYKLEREIAAYIKKQLDVSQGETWHVIVGKNFGSYVTHEKGYFVYFYIGPLA
SQ  FLVFKTA
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