ID  Q6KAR6;
PN  Exocyst complex component 3;
GN  Exoc3;
OS  10090;
SL  Nucleus Position: SL-0198;
SL  Comments: Cytoplasm {ECO:0000250|UniProtKB:O54921}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:O54921}. Cell projection, growth cone {ECO:0000250|UniProtKB:O54921}. Midbody {ECO:0000250|UniProtKB:O60645}. Golgi apparatus {ECO:0000250|UniProtKB:O60645}. Cell projection, neuron projection {ECO:0000250|UniProtKB:Q62825}. Note=Perinuclear in undifferentiated cells. Redistributes to growing neurites and growth cones during neuronal differentiation (By similarity). During mitosis, early recruitment to the midbody requires RALA, but not RALB, and EXOC2. In late stages of cytokinesis, localization to the midbody is RALB- dependent (By similarity). {ECO:0000250|UniProtKB:O54921, ECO:0000250|UniProtKB:O60645}.
DR  UNIPROT: Q6KAR6;
DR  Pfam: PF06046;
DE  Function: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. {ECO:0000250}.
DE  Reference Proteome: Yes;
DE  Interaction: P25322; IntAct: EBI-3956307; Score: 0.46
DE  Interaction: O35382; IntAct: EBI-8299949; Score: 0.40
DE  Interaction: P23819; IntAct: EBI-8300089; Score: 0.40
DE  Interaction: P35438; IntAct: EBI-8300130; Score: 0.40
DE  Interaction: P11234; IntAct: EBI-3956345; Score: 0.27
GO  GO:0000145;
GO  GO:0005794;
GO  GO:0030426;
GO  GO:0030496;
GO  GO:0048471;
GO  GO:0042734;
GO  GO:0030667;
GO  GO:0000149;
GO  GO:0051601;
GO  GO:0006887;
GO  GO:0090148;
GO  GO:0000281;
GO  GO:0015031;
GO  GO:0006904;
GO  GO:0090522;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MCKDSACFLTMKETDLEAVATAVQRVAGMLQRPDQLDKVEQYRRREARKKASVEARLKAAIQSQLDGVRTGLSQLHNALN
SQ  DVKDIQQSLADVSKDWRQSINTIESLKDVKDAVVQHSQLAAAVENLKNIFSVPEIVRETQDLIEQGALLQAHRKLMDLEC
SQ  SRDGLMCEQYRMDSGNKRDMTLIHGYFGSTQGLSDELAKQLWMVLQRSLVTVRRDPTLLVSVVRIIEREEKIDRRILDRK
SQ  KQTGFVPPGRPKNWKEKMFAILDRTVTTRIEGTQADTRESDKMWLVRHLEIIRKYVLDDLIVAKNLMVQCFPPHYEIFKN
SQ  LLSMYHQALSTRMQDLASEDLEANEIVSLLTWVLNTYTSAEMMGNVELAPEVDVSALEPLLSPNIVSELLDTYMSTLTSN
SQ  IIAWLRKALETDKKDWSKETEPEADQDGYYQTTLPAIVFQMFEQNLQVAAQISEDLKTKVLVLCLQQMNSFLSRYKDEAQ
SQ  LYKEEHLRNRQHPHCYVQYMIAIINNCQTFKESIISLKRKYLKTEAEEGLCLSQPSMDGILDAIAKEGCSSLLEEVFLDL
SQ  EQHLNELMTKKWLLGSNAVDIICVTVEDYFNDFAKIKKPYKKRMTAEAHRRVVVEYLRAVMQKRISFRSAEERKEGAEKM
SQ  VREAEQLRFLFRKLASGFGEDADGHCDTIVAVAEVIKLTDPSLLYLEVSTLVSKYPDIRDDHIGALLALRGDASRDMKQT
SQ  IMETLEQGPMQASPNYVPIFKEIVVPSLNVAKLLK
//