ID  Q7TQE6;
PN  Macoilin;
GN  Maco1;
OS  10090;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0182;
SL  Comments: Rough endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P91193}; Multi-pass membrane protein {ECO:0000255}. Nucleus membrane {ECO:0000250|UniProtKB:P91193}; Multi- pass membrane protein {ECO:0000255}. Note=Detected in the nucleus membrane of non-neuronal cells and in axonal outgrowths of neuronal cells (PubMed:15255972). {ECO:0000269|PubMed:15255972}.
DR  UNIPROT: Q7TQE6;
DR  Pfam: PF09726;
DE  Function: Plays a role in the regulation of neuronal activity. {ECO:0000250|UniProtKB:Q8N5G2}.
DE  Reference Proteome: Yes;
DE  Interaction: Q5F2C3; IntAct: EBI-20739590; Score: 0.37
GO  GO:0030424;
GO  GO:0016021;
GO  GO:0043005;
GO  GO:0044306;
GO  GO:0031965;
GO  GO:0005634;
GO  GO:0030867;
GO  GO:0045202;
GO  GO:0008017;
GO  GO:0007420;
GO  GO:0006935;
GO  GO:0023041;
TP  Membrane Topology: Transmembrane; Source: UniProt - Sequence Analysis {ECO:0000255};
SQ  MKRRNADCSKLRRPLKRNRITEGIYGSTFLYLKFLVVWALVLLADFVLEFRFEYLWPFWLFIRSVYDSFRYQGLAFSVFF
SQ  VCVAFTSNIICLLFIPIQWLFFAASTYVWVQYVWHTERGVCLPTVSLWILFVYIEAAIRFKDLKNFHVDLCRPFAAHCIG
SQ  YPVVTLGFGFKSYVSYKMRLRKQKEVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPAN
SQ  KKLSTTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKRLNNDLVGSTENLLKEDSCTASSK
SQ  NYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKGPSAHKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQAS
SQ  RQVEQELRSQISALSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKR
SQ  KKLEEATAARAVAFAAASRGECTETLRSRIRELEAEGKKLTMDMKVKEEQIRELELKVQELRKYKENEKDTEVLMSALSA
SQ  MQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQKIAEVMAVMPSITYSAATSPLSPVSPHY
SQ  SSKFVETSPSGLDPNASVYQPLKK
//