ID  Q80XQ8;
PN  Myelin-associated neurite-outgrowth inhibitor;
GN  Fam168b;
OS  10090;
SL  Nucleus Position: SL-0198;
SL  Comments: Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:D4AEP3}. Cell membrane {ECO:0000269|PubMed:20716133}; Multi-pass membrane protein {ECO:0000269|PubMed:20716133}. Cell projection, axon {ECO:0000269|PubMed:20716133}. Note=Expressed in neuronal cell bodies and axonal fibers. {ECO:0000269|PubMed:20716133}.
DR  UNIPROT: Q80XQ8;
DR  UNIPROT: Q3UNC7;
DR  UNIPROT: Q5DTR7;
DR  Pfam: PF14944;
DE  Function: Inhibitor of neuronal axonal outgrowth. Acts as a negative regulator of CDC42 and STAT3 and a positive regulator of STMN2. Positive regulator of CDC27. {ECO:0000269|PubMed:20716133}.
DE  Reference Proteome: Yes;
GO  GO:0030424;
GO  GO:0016021;
GO  GO:0048471;
GO  GO:0005886;
TP  Membrane Topology: Transmembrane; Source: UniProt - Sequence Analysis {ECO:0000255};
SQ  MNPVYSPGSSGVPYANAKGIGYPAGFPVGYAAAPAYSPNMYPGANPTFQTGYTPGTPYKVSCSPTSGAVPPYSSSPNPYQ
SQ  TAVYPVRSAYPQQSPYAQQGTYYTQPLYAAPPHVIHHTTVVQPNGMPATVYPAPIPPPRGSGVTMGMVAGTTMAMSAGTL
SQ  LTAHSPTPVAPHPVTVPTYRAPGTPTYSYVPPQW
//