ID  Q86YD1;
PN  Prostate tumor-overexpressed gene 1 protein;
GN  PTOV1;
OS  9606;
SL  Nucleus Position: SL-0198;
SL  Comments: Cytoplasm {ECO:0000269|PubMed:12598323, ECO:0000269|PubMed:16639697}. Nucleus {ECO:0000269|PubMed:12598323, ECO:0000269|PubMed:15713644}. Cell membrane {ECO:0000269|PubMed:15713644}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:11313889}. Note=Translocates from the cytoplasm to the nucleus at the onset of S-phase (PubMed:12598323). Also localizes to lipid rafts (PubMed:15713644). {ECO:0000269|PubMed:12598323, ECO:0000269|PubMed:15713644}.
DR  UNIPROT: Q86YD1;
DR  UNIPROT: Q6UXX7;
DR  UNIPROT: Q96BU3;
DR  UNIPROT: Q9HBN4;
DR  UNIPROT: Q9NYL1;
DR  Pfam: PF11232;
DR  OMIM: 610195;
DR  DisGeNET: 53635;
DE  Function: May activate transcription. Required for nuclear translocation of FLOT1. Promotes cell proliferation. {ECO:0000269|PubMed:12598323, ECO:0000269|PubMed:15713644, ECO:0000269|PubMed:17641689}.
DE  Reference Proteome: Yes;
DE  Interaction: Q08495; IntAct: EBI-735504; Score: 0.00
DE  Interaction: Q13526; IntAct: EBI-735507; Score: 0.00
DE  Interaction: Q13813; IntAct: EBI-735510; Score: 0.00
DE  Interaction: O75069; IntAct: EBI-737468; Score: 0.00
DE  Interaction: P31947; IntAct: EBI-7544614; Score: 0.40
DE  Interaction: Q14457; IntAct: EBI-3257986; Score: 0.35
DE  Interaction: P0DOE9; IntAct: EBI-6138583; Score: 0.35
DE  Interaction: Q13617; IntAct: EBI-21327106; Score: 0.35
DE  Interaction: O75901; IntAct: EBI-6912184; Score: 0.35
DE  Interaction: Q16659; IntAct: EBI-12502733; Score: 0.35
DE  Interaction: P57078; IntAct: EBI-12503575; Score: 0.35
DE  Interaction: Q04917; IntAct: EBI-11003456; Score: 0.35
DE  Interaction: O94776; IntAct: EBI-11903853; Score: 0.00
DE  Interaction: Q13547; IntAct: EBI-11912782; Score: 0.00
DE  Interaction: P48380; IntAct: EBI-11921171; Score: 0.00
DE  Interaction: Q9H1B5; IntAct: EBI-11931253; Score: 0.00
DE  Interaction: Q9Y3I0; IntAct: EBI-11940521; Score: 0.00
DE  Interaction: Q8IYS4; IntAct: EBI-21565697; Score: 0.35
DE  Interaction: Q9Y2U9; IntAct: EBI-21781475; Score: 0.35
DE  Interaction: P40855; IntAct: EBI-21782948; Score: 0.35
DE  Interaction: P27348; IntAct: EBI-21902679; Score: 0.35
DE  Interaction: P61981; IntAct: EBI-21905461; Score: 0.35
DE  Interaction: P51679; IntAct: EBI-20804528; Score: 0.37
DE  Interaction: P0DTC9; IntAct: EBI-27127583; Score: 0.35
GO  GO:0005654;
GO  GO:0048471;
GO  GO:0005886;
GO  GO:0005667;
GO  GO:0045944;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MVRPRRAPYRSGAGGPLGGRGRPPRPLVVRAVRSRSWPASPRGPQPPRIRARSAPPMEGARVFGALGPIGPSSPGLTLGG
SQ  LAVSEHRLSNKLLAWSGVLEWQEKRRPYSDSTAKLKRTLPCQAYVNQGENLETDQWPQKLIMQLIPQQLLTTLGPLFRNS
SQ  QLAQFHFTNRDCDSLKGLCRIMGNGFAGCMLFPHISPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVSAIRQVITTRKQAV
SQ  GPGGVNSGPVQIVNNKFLAWSGVMEWQEPRPEPNSRSKRWLPSHVYVNQGEILRTEQWPRKLYMQLIPQQLLTTLVPLFR
SQ  NSRLVQFHFTKDLETLKSLCRIMDNGFAGCVHFSYKASCEIRVLMLLYSSEKKIFIGLIPHDQGNFVNGIRRVIANQQQV
SQ  LQRNLEQEQQQRGMGG
//