ID  Q8C1E7;
PN  Ion channel TACAN;
GN  Tmem120a;
OS  10090;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0179;
SL  Nucleus Position: SL-0182;
SL  Comments: Cell membrane {ECO:0000269|PubMed:32084332}; Multi-pass membrane protein {ECO:0000255}. Nucleus inner membrane {ECO:0000269|PubMed:20091084}; Multi-pass membrane protein {ECO:0000255}.
DR  UNIPROT: Q8C1E7;
DR  UNIPROT: Q8BWP7;
DR  PDB: 7N0K;
DR  PDB: 7N0L;
DR  Pfam: PF07851;
DE  Function: Ion channel involved in sensing mechanical pain (PubMed:32084332). Contributes to mechanosensitive currents in nocireceptors and detecting mechanical pain stimuli (PubMed:32084332). May also be required for efficient adipogenesis (PubMed:26024229). {ECO:0000269|PubMed:26024229, ECO:0000269|PubMed:32084332}.
DE  Reference Proteome: Yes;
GO  GO:0016021;
GO  GO:0016020;
GO  GO:0005637;
GO  GO:0005886;
GO  GO:0005216;
GO  GO:0050966;
GO  GO:0045444;
GO  GO:0034220;
GO  GO:0051291;
GO  GO:0051260;
TP  Membrane Topology: Transmembrane; Source: UniProt - Sequence Analysis {ECO:0000255};
SQ  MQSPPPDPLGDCLRNWEDLQQDFQGIQETHRLYRLKLEELTKLQANCTNSITRQKKRLQELALVLKKCRPSLPSESMEAA
SQ  QELENQMKERQGLFFDMEAYLPKKNGLYLSLVLGNVNVTLLSKQAKFAYKDEYEKFKLYLTIILIVISFTCRFLLNSRVT
SQ  DAAFNFLLVWYYCTLTIRESILINNGSRIKGWWVFHHYVSTFLSGVMLTWPDGLMYQKFRNQFLSFSMYQSFVQFLQYYY
SQ  QSGCLYRLRALGERHTMDLTVEGFQSWMWRGLTFLLPFLFFGHFWQLFNALTLFNLARDPECKEWQVLMCGFPFLLLFLG
SQ  NFFTTLRVVHQKFHSQQHGNKKD
//