ID  Q8IWB1;
PN  Inositol 1,4,5-trisphosphate receptor-interacting protein;
GN  ITPRIP;
OS  9606;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0182;
SL  Nucleus Position: SL-0183;
SL  Comments: Cell membrane {ECO:0000269|PubMed:16990268}; Single-pass type I membrane protein. Nucleus outer membrane {ECO:0000250|UniProtKB:Q3TNL8}; Single-pass type I membrane protein {ECO:0000255}.
DR  UNIPROT: Q8IWB1;
DR  UNIPROT: D3DRA5;
DR  UNIPROT: Q5JU17;
DR  UNIPROT: Q96MS8;
DR  UNIPROT: Q9C0A9;
DR  Pfam: PF03281;
DR  DisGeNET: 85450;
DE  Function: Enhances Ca(2+)-mediated inhibition of inositol 1,4,5- triphosphate receptor (ITPR) Ca(2+) release. {ECO:0000269|PubMed:16990268}.
DE  Reference Proteome: Yes;
DE  Interaction: O15173; IntAct: EBI-23781080; Score: 0.56
DE  Interaction: Q99MK9; IntAct: EBI-2556403; Score: 0.40
DE  Interaction: Q9NS23; IntAct: EBI-6912010; Score: 0.35
DE  Interaction: Q8K2C9; IntAct: EBI-9379702; Score: 0.40
DE  Interaction: Q9HB71; IntAct: EBI-9379744; Score: 0.40
DE  Interaction: Q9BPW0; IntAct: EBI-9379763; Score: 0.40
DE  Interaction: Q3UJD6; IntAct: EBI-9379723; Score: 0.40
DE  Interaction: Q96EQ0; IntAct: EBI-24531039; Score: 0.56
DE  Interaction: Q86WH2; IntAct: EBI-23878826; Score: 0.56
DE  Interaction: Q8WXA8; IntAct: EBI-21508371; Score: 0.35
DE  Interaction: P04201; IntAct: EBI-21538834; Score: 0.35
DE  Interaction: Q86T26; IntAct: EBI-21582478; Score: 0.35
DE  Interaction: Q8WW62; IntAct: EBI-21589315; Score: 0.35
DE  Interaction: Q96FT7; IntAct: EBI-21589962; Score: 0.35
DE  Interaction: Q92187; IntAct: EBI-21641713; Score: 0.35
DE  Interaction: P62195; IntAct: EBI-21656272; Score: 0.35
DE  Interaction: Q9Y5F2; IntAct: EBI-21658599; Score: 0.35
DE  Interaction: P40259; IntAct: EBI-21668943; Score: 0.35
DE  Interaction: P29016; IntAct: EBI-21693940; Score: 0.35
DE  Interaction: P46098; IntAct: EBI-21749232; Score: 0.35
DE  Interaction: Q96GX1; IntAct: EBI-21777303; Score: 0.35
DE  Interaction: Q6PIU2; IntAct: EBI-21801768; Score: 0.35
DE  Interaction: Q86YC3; IntAct: EBI-21811436; Score: 0.35
DE  Interaction: O60603; IntAct: EBI-21859955; Score: 0.35
DE  Interaction: P55058; IntAct: EBI-21861097; Score: 0.35
DE  Interaction: Q4U2R8; IntAct: EBI-21864696; Score: 0.35
DE  Interaction: Q9NZ94; IntAct: EBI-16423332; Score: 0.54
GO  GO:0016021;
GO  GO:0016020;
GO  GO:0005640;
GO  GO:0005886;
GO  GO:0004860;
GO  GO:0008625;
GO  GO:1902042;
TP  Membrane Topology: Transmembrane; Source: UniProt - Sequence Analysis {ECO:0000255};
SQ  MAMGLFRVCLVVVTAIINHPLLFPRENATVPENEEEIIRKMQAHQEKLQLEQLRLEEEVARLAAEKEALEQVAEEGRQQN
SQ  ETRVAWDLWSTLCMILFLMIEVWRQDHQEGPSPECLGGEEDELPGLGGAPLQGLTLPNKATLGHFYERCIRGATADAART
SQ  REFLEGFVDDLLEALRSLCNRDTDMEVEDFIGVDSMYENWQVDRPLLCHLFVPFTPPEPYRFHPELWCSGRSVPLDRQGY
SQ  GQIKVVRADGDTLSCICGKTKLGEDMLCLLHGRNSMAPPCGDMENLLCATDSLYLDTMQVMKWFQTALTRAWKGIAHKYE
SQ  FDLAFGQLDSPGSLKIKFRSGKFMPFNLIPVIQCDDSDLYFVSHLPREPSEGTPASSTDWLLSFAVYERHFLRTTLKALP
SQ  EGACHLSCLQIASFLLSKQSRLTGPSGLSSYHLKTALLHLLLLRQAADWKAGQLDARLHELLCFLEKSLLQKKLHHFFIG
SQ  NRKVPEAMGLPEAVLRAEPLNLFRPFVLQRSLYRKTLDSFYEMLKNAPALISEYSLHVPSDQPTPKS
//