ID  Q8NC51;
PN  Plasminogen activator inhibitor 1 RNA-binding protein;
GN  SERBP1;
OS  9606;
SL  Nucleus Position: SL-0198;
SL  Comments: Cytoplasm {ECO:0000269|PubMed:12505151, ECO:0000269|PubMed:28695742}. Nucleus {ECO:0000269|PubMed:12505151, ECO:0000269|PubMed:28695742}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:12505151}.
DR  UNIPROT: Q8NC51;
DR  UNIPROT: Q5VU19;
DR  UNIPROT: Q5VU20;
DR  UNIPROT: Q5VU22;
DR  UNIPROT: Q8WUH0;
DR  UNIPROT: Q96SE2;
DR  UNIPROT: Q9BTY3;
DR  UNIPROT: Q9BUM4;
DR  UNIPROT: Q9Y367;
DR  UNIPROT: Q9Y4S3;
DR  PDB: 4V6X;
DR  PDB: 6Z6M;
DR  PDB: 6Z6N;
DR  Pfam: PF04774;
DR  Pfam: PF16174;
DR  OMIM: 607378;
DR  DisGeNET: 26135;
DE  Function: May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay. Seems to play a role in PML-nuclear bodies formation (PubMed:28695742). {ECO:0000269|PubMed:11001948, ECO:0000269|PubMed:28695742}.
DE  Reference Proteome: Yes;
DE  Interaction: A0A142I5B9; IntAct: EBI-20625330; Score: 0.35
DE  Interaction: P0DTD1; IntAct: EBI-25509548; Score: 0.35
DE  Interaction: Q06787; IntAct: EBI-8844408; Score: 0.35
DE  Interaction: Q12873; IntAct: EBI-523588; Score: 0.58
DE  Interaction: Q53HC9; IntAct: EBI-1064285; Score: 0.00
DE  Interaction: P62330; IntAct: EBI-1068138; Score: 0.00
DE  Interaction: Q15654; IntAct: EBI-1069923; Score: 0.00
DE  Interaction: P01889; IntAct: EBI-1076169; Score: 0.00
DE  Interaction: Q14164; IntAct: EBI-1079918; Score: 0.00
DE  Interaction: O75815; IntAct: EBI-1080874; Score: 0.00
DE  Interaction: O94817; IntAct: EBI-1085290; Score: 0.00
DE  Interaction: P32121; IntAct: EBI-1642567; Score: 0.35
DE  Interaction: Q00005; IntAct: EBI-2211497; Score: 0.35
DE  Interaction: Q8AZK7; IntAct: EBI-9632715; Score: 0.35
DE  Interaction: O15264; IntAct: EBI-2255044; Score: 0.35
DE  Interaction: P52735; IntAct: EBI-2654400; Score: 0.00
DE  Interaction: P01100; IntAct: EBI-2679744; Score: 0.00
DE  Interaction: P14921; IntAct: EBI-2680135; Score: 0.00
DE  Interaction: A0A6L8PVV9; IntAct: EBI-2828099; Score: 0.00
DE  Interaction: A0A5P8YLY5; IntAct: EBI-2861962; Score: 0.00
DE  Interaction: Q92731; IntAct: EBI-2880601; Score: 0.35
DE  Interaction: Q9H492; IntAct: EBI-3044058; Score: 0.35
DE  Interaction: Q9GZQ8; IntAct: EBI-3045543; Score: 0.35
DE  Interaction: P60520; IntAct: EBI-3046676; Score: 0.35
DE  Interaction: Q9H0R8; IntAct: EBI-3048562; Score: 0.35
DE  Interaction: O95166; IntAct: EBI-3050465; Score: 0.35
DE  Interaction: Q8TB96; IntAct: EBI-7383128; Score: 0.37
DE  Interaction: P68400; IntAct: EBI-5322101; Score: 0.44
DE  Interaction: Q0HD54; IntAct: EBI-6155110; Score: 0.35
DE  Interaction: Q77M19; IntAct: EBI-6270503; Score: 0.35
DE  Interaction: Q86VP6; IntAct: EBI-21322532; Score: 0.35
DE  Interaction: Q13616; IntAct: EBI-21323857; Score: 0.35
DE  Interaction: Q15843; IntAct: EBI-21328206; Score: 0.35
DE  Interaction: Q13618; IntAct: EBI-21329068; Score: 0.35
DE  Interaction: Q9NR22; IntAct: EBI-8481541; Score: 0.37
DE  Interaction: O35182; IntAct: EBI-8456591; Score: 0.35
DE  Interaction: Q4VGL6; IntAct: EBI-8759371; Score: 0.35
DE  Interaction: P0C090; IntAct: EBI-8759987; Score: 0.35
DE  Interaction: Q99873; IntAct: EBI-8844279; Score: 0.35
DE  Interaction: P09651; IntAct: EBI-8844279; Score: 0.43
DE  Interaction: Q01844; IntAct: EBI-8844325; Score: 0.35
DE  Interaction: P51116; IntAct: EBI-8844325; Score: 0.35
DE  Interaction: P19338; IntAct: EBI-8845229; Score: 0.27
DE  Interaction: P31483; IntAct: EBI-8844366; Score: 0.27
DE  Interaction: P67809; IntAct: EBI-8853354; Score: 0.50
DE  Interaction: Q8NC51; IntAct: EBI-10486506; Score: 0.37
DE  Interaction: Q16666; IntAct: EBI-9995438; Score: 0.35
DE  Interaction: P05412; IntAct: EBI-11323169; Score: 0.35
DE  Interaction: P03182; IntAct: EBI-11721938; Score: 0.35
DE  Interaction: Q6ZWV7; IntAct: EBI-10997876; Score: 0.35
DE  Interaction: P23116; IntAct: EBI-11020127; Score: 0.35
DE  Interaction: Q9D287; IntAct: EBI-11022935; Score: 0.35
DE  Interaction: P27635; IntAct: EBI-11035646; Score: 0.35
DE  Interaction: Q99PL5; IntAct: EBI-11066888; Score: 0.35
DE  Interaction: Q00839; IntAct: EBI-11088773; Score: 0.35
DE  Interaction: P06748; IntAct: EBI-11145880; Score: 0.35
DE  Interaction: P19712; IntAct: EBI-10901232; Score: 0.35
DE  Interaction: Q9NRD5; IntAct: EBI-24463602; Score: 0.56
DE  Interaction: Q9NZI8; IntAct: EBI-13949271; Score: 0.35
DE  Interaction: Q15813; IntAct: EBI-21887754; Score: 0.40
DE  Interaction: Q9BTM9; IntAct: EBI-15902832; Score: 0.35
DE  Interaction: Q6ZNJ1; IntAct: EBI-16749633; Score: 0.35
DE  Interaction: P09622; IntAct: EBI-20304669; Score: 0.35
DE  Interaction: O00429; IntAct: EBI-20305770; Score: 0.35
DE  Interaction: Q99497; IntAct: EBI-20306366; Score: 0.35
DE  Interaction: Q99714; IntAct: EBI-20306067; Score: 0.35
DE  Interaction: P08559; IntAct: EBI-20306509; Score: 0.35
DE  Interaction: P31040; IntAct: EBI-20306992; Score: 0.35
DE  Interaction: P35610; IntAct: EBI-20307233; Score: 0.35
DE  Interaction: Q9HCE5; IntAct: EBI-20595531; Score: 0.35
DE  Interaction: P52298; IntAct: EBI-20623424; Score: 0.35
DE  Interaction: P51957; IntAct: EBI-20721387; Score: 0.35
DE  Interaction: P10636; IntAct: EBI-20798291; Score: 0.35
DE  Interaction: P05067; IntAct: EBI-20821761; Score: 0.35
DE  Interaction: Q969X2; IntAct: EBI-20903424; Score: 0.40
DE  Interaction: P30622; IntAct: EBI-20908792; Score: 0.40
DE  Interaction: P15918; IntAct: EBI-20921596; Score: 0.40
DE  Interaction: P46783; IntAct: EBI-20931200; Score: 0.40
DE  Interaction: Q5VT25; IntAct: EBI-20938284; Score: 0.40
DE  Interaction: A2A935; IntAct: EBI-21022882; Score: 0.35
DE  Interaction: P14404; IntAct: EBI-21026252; Score: 0.35
DE  Interaction: O96013; IntAct: EBI-26962273; Score: 0.35
DE  Interaction: P61981; IntAct: EBI-26966879; Score: 0.35
DE  Interaction: Q5S007; IntAct: EBI-21360986; Score: 0.35
DE  Interaction: F5H7Q8; IntAct: EBI-21261537; Score: 0.35
DE  Interaction: O95183; IntAct: EBI-21267749; Score: 0.35
DE  Interaction: P03372; IntAct: EBI-21301141; Score: 0.35
DE  Interaction: P13569; IntAct: EBI-25416349; Score: 0.35
DE  Interaction: Q16828; IntAct: EBI-25377680; Score: 0.35
DE  Interaction: P06241; IntAct: EBI-25385167; Score: 0.35
DE  Interaction: P0DOF2; IntAct: EBI-25603126; Score: 0.35
DE  Interaction: P41229; IntAct: EBI-25480257; Score: 0.35
DE  Interaction: P69479; IntAct: EBI-25568051; Score: 0.35
DE  Interaction: Q8NHP6; IntAct: EBI-25617558; Score: 0.35
DE  Interaction: P50454; IntAct: EBI-25836558; Score: 0.56
DE  Interaction: P16284; IntAct: EBI-25881385; Score: 0.56
DE  Interaction: P37173; IntAct: EBI-25892860; Score: 0.56
DE  Interaction: Q09161; IntAct: EBI-26396507; Score: 0.35
DE  Interaction: P14240; IntAct: EBI-26968430; Score: 0.35
DE  Interaction: Q99608; IntAct: EBI-26955247; Score: 0.27
DE  Interaction: P0DTC9; IntAct: EBI-26994159; Score: 0.35
DE  Interaction: Q13363; IntAct: EBI-27044482; Score: 0.35
DE  Interaction: F1PAA9; IntAct: EBI-27079701; Score: 0.27
DE  Interaction: P35226; IntAct: EBI-27108918; Score: 0.35
DE  Interaction: Q99592; IntAct: EBI-27093179; Score: 0.35
GO  GO:0005737;
GO  GO:0005829;
GO  GO:0070062;
GO  GO:0016020;
GO  GO:0005634;
GO  GO:0048471;
GO  GO:0045296;
GO  GO:0003730;
GO  GO:0043022;
GO  GO:0003723;
GO  GO:0032183;
GO  GO:0030578;
GO  GO:0043488;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQTNSNAAGKQLRKESQKDRKN
SQ  PLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGEGKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDR
SQ  PIRGRGGLGRGRGGRGRGMGRGDGFDSRGKREFDRHSGSDRSSFSHYSGLKHEDKRGGSGSHNWGTVKDELTESPKYIQK
SQ  QISYNYSDLDQSNVTEETPEGEEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKDRAKVEFNIRKPNEGADGQWK
SQ  KGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFGDLGRPGRGGRGGRGGRGRGGRPNRGSRTDKSSASAPDVDD
SQ  PEAFPALA
//