ID  Q8NFH3;
PN  Nucleoporin Nup43;
GN  NUP43;
OS  9606;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0185;
SL  Comments: Chromosome, centromere, kinetochore. Nucleus, nuclear pore complex.
DR  UNIPROT: Q8NFH3;
DR  UNIPROT: B4E2F0;
DR  UNIPROT: Q9H8S0;
DR  PDB: 4I79;
DR  PDB: 5A9Q;
DR  PDB: 7PEQ;
DR  Pfam: PF00400;
DR  PROSITE: PS00678;
DR  PROSITE: PS50082;
DR  PROSITE: PS50294;
DR  OMIM: 608141;
DR  DisGeNET: 348995;
DE  Function: Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. {ECO:0000269|PubMed:17363900}.
DE  Reference Proteome: Yes;
DE  Interaction: A0A142I5B9; IntAct: EBI-20625330; Score: 0.35
DE  Interaction: P02545; IntAct: EBI-16795756; Score: 0.27
DE  Interaction: P49790; IntAct: EBI-11076796; Score: 0.35
DE  Interaction: P52948; IntAct: EBI-21865034; Score: 0.35
DE  Interaction: P55735; IntAct: EBI-21865034; Score: 0.53
DE  Interaction: P57740; IntAct: EBI-11160436; Score: 0.64
DE  Interaction: Q12769; IntAct: EBI-21865034; Score: 0.35
DE  Interaction: Q14974; IntAct: EBI-11115566; Score: 0.35
DE  Interaction: Q6PFD9; IntAct: EBI-2563676; Score: 0.56
DE  Interaction: Q80U93; IntAct: EBI-11014856; Score: 0.35
DE  Interaction: Q8BH74; IntAct: EBI-2563157; Score: 0.56
DE  Interaction: P01889; IntAct: EBI-1083368; Score: 0.00
DE  Interaction: Q96S44; IntAct: EBI-6256589; Score: 0.53
DE  Interaction: Q8WYP5; IntAct: EBI-9050503; Score: 0.49
DE  Interaction: Q9BW27; IntAct: EBI-9032422; Score: 0.76
DE  Interaction: Q99P88; IntAct: EBI-10997466; Score: 0.35
DE  Interaction: Q9ERU9; IntAct: EBI-10999306; Score: 0.35
DE  Interaction: Q8VE37; IntAct: EBI-11043815; Score: 0.35
DE  Interaction: P63280; IntAct: EBI-11044140; Score: 0.35
DE  Interaction: Q96EE3; IntAct: EBI-11086798; Score: 0.67
DE  Interaction: Q9BPU9; IntAct: EBI-11377507; Score: 0.27
DE  Interaction: Q8IVT5; IntAct: EBI-14035152; Score: 0.35
DE  Interaction: Q9NPF4; IntAct: EBI-21527449; Score: 0.35
DE  Interaction: Q9UBP0; IntAct: EBI-21757061; Score: 0.35
DE  Interaction: P23025; IntAct: EBI-21837437; Score: 0.35
DE  Interaction: Q9Y3C4; IntAct: EBI-21865034; Score: 0.35
DE  Interaction: Q9NSK0; IntAct: EBI-21865034; Score: 0.35
DE  Interaction: Q9H0B6; IntAct: EBI-21865034; Score: 0.35
DE  Interaction: Q92526; IntAct: EBI-21865034; Score: 0.35
DE  Interaction: Q8WUM0; IntAct: EBI-21865034; Score: 0.53
DE  Interaction: Q8NFH4; IntAct: EBI-21865034; Score: 0.53
DE  Interaction: Q14657; IntAct: EBI-21865034; Score: 0.35
DE  Interaction: P33176; IntAct: EBI-21865034; Score: 0.35
DE  Interaction: Q96I36; IntAct: EBI-16791250; Score: 0.27
DE  Interaction: Q9Y6K9; IntAct: EBI-20737021; Score: 0.35
DE  Interaction: Q8IY21; IntAct: EBI-21259607; Score: 0.35
DE  Interaction: P37802; IntAct: EBI-25482076; Score: 0.35
DE  Interaction: P57721; IntAct: EBI-25482076; Score: 0.35
DE  Interaction: P55212; IntAct: EBI-25836238; Score: 0.56
DE  Interaction: P06307; IntAct: EBI-25837221; Score: 0.56
DE  Interaction: P07686; IntAct: EBI-25867165; Score: 0.56
DE  Interaction: P13473; IntAct: EBI-25874611; Score: 0.56
DE  Interaction: P02766; IntAct: EBI-25894354; Score: 0.56
DE  Interaction: Q99497; IntAct: EBI-25913824; Score: 0.56
DE  Interaction: O75400; IntAct: EBI-25924971; Score: 0.56
DE  Interaction: P54252; IntAct: EBI-25974688; Score: 0.56
DE  Interaction: P54253; IntAct: EBI-25977247; Score: 0.56
DE  Interaction: Q13148; IntAct: EBI-25984820; Score: 0.56
GO  GO:0005829;
GO  GO:0000776;
GO  GO:0005635;
GO  GO:0005643;
GO  GO:0031080;
GO  GO:0016607;
GO  GO:0005654;
GO  GO:0007049;
GO  GO:0051301;
GO  GO:0007059;
GO  GO:0051028;
GO  GO:0006913;
GO  GO:0015031;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MEEIYAKFVSQKISKTRWRPLPPGSLQTAETFATGSWDNEENYISLWSIGDFGNLDSDGGFEGDHQLLCDIRHHGDVMDL
SQ  QFFDQERIVAASSTGCVTVFLHHPNNQTLSVNQQWTTAHYHTGPGSPSYSSAPCTGVVCNNPEIVTVGEDGRINLFRADH
SQ  KEAVRTIDNADSSTLHAVTFLRTPEILTVNSIGQLKIWDFRQQGNEPSQILSLTGDRVPLHCVDRHPNQQHVVATGGQDG
SQ  MLSIWDVRQGTMPVSLLKAHEAEMWEVHFHPSNPEHLFTCSEDGSLWHWDASTDVPEKSSLFHQGGRSSTFLSHSISNQA
SQ  NVHQSVISSWLSTDPAKDRIEITSLLPSRSLSVNTLDVLGPCLVCGTDAEAIYVTRHLFS
//