ID  Q8R1T1;
PN  Charged multivesicular body protein 7;
GN  Chmp7;
OS  10090;
SL  Nucleus Position: SL-0178;
SL  Comments: Cytoplasm {ECO:0000250|UniProtKB:Q8WUX9}. Nucleus envelope {ECO:0000250|UniProtKB:Q8WUX9}. Note=Diffused localization, with some punctate distribution, especially in the perinuclear area. Localizes to the reforming nuclear envelope on chromatin disks during late anaphase. {ECO:0000250|UniProtKB:Q8WUX9}.
DR  UNIPROT: Q8R1T1;
DR  UNIPROT: Q8CFW4;
DR  Pfam: PF03357;
DE  Function: ESCRT-III-like protein required to recruit the ESCRT-III complex to the nuclear envelope (NE) during late anaphase (By similarity). Together with SPAST, the ESCRT-III complex promotes NE sealing and mitotic spindle disassembly during late anaphase (By similarity). Recruited to the reforming NE during anaphase by LEMD2 (By similarity). Plays a role in the endosomal sorting pathway (By similarity). {ECO:0000250|UniProtKB:Q8WUX9}.
DE  Reference Proteome: Yes;
GO  GO:1904930;
GO  GO:0000421;
GO  GO:0000785;
GO  GO:0005829;
GO  GO:0000815;
GO  GO:0000776;
GO  GO:0005828;
GO  GO:0005765;
GO  GO:0030496;
GO  GO:0005771;
GO  GO:0032585;
GO  GO:0005635;
GO  GO:0005643;
GO  GO:0005654;
GO  GO:0005886;
GO  GO:0097352;
GO  GO:0006914;
GO  GO:0010458;
GO  GO:1902774;
GO  GO:0045324;
GO  GO:0032511;
GO  GO:0090148;
GO  GO:0061952;
GO  GO:0007080;
GO  GO:0036258;
GO  GO:0071985;
GO  GO:0061763;
GO  GO:0060548;
GO  GO:0031468;
GO  GO:0006997;
GO  GO:0001778;
GO  GO:0071168;
GO  GO:0015031;
GO  GO:1901673;
GO  GO:0043162;
GO  GO:0006900;
GO  GO:0051469;
GO  GO:0046761;
GO  GO:0039702;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MWSPEREAQAPTGGDPAGLLPPEWEEDEERMSFLFSAFKRSREVNSTDWDSKMGFWAPLVLSHSRRQGVVRLRLRDLQEA
SQ  FQRKGSVPLGLATVLQDLLRRGELQRESDFMASVDSSWISWGVGVFLLKPLKWTLSNMLGDHKVPAEEVLVAVELLKEKA
SQ  EEVYRLYQNSPLSSHPVVALSELSALCANSCPDERTFYLVLLQLQKEKRVTVLEQNGEKIVKFARGPHAKVSPVNDVDVG
SQ  VYQLMQSEQLLSRKVESLSQESERCKEEARRACRAGKKQLALRSLKAKQRTEKRIEALHAKLDTVQGILDRIYASQTDQM
SQ  VFNAYQAGVGALKLSMKDVTVEKAESLVDQIQELCDTQDEVSQTLAGGVTNGLDFDSEELEKELDILLQDTTTEPLSLLE
SQ  TPQETTLYTNSVPKPRILDAELEAELEKLSLSEGGLIPSSKSPKRQLEPTL
//