ID  Q8R4T5;
PN  General receptor for phosphoinositides 1-associated scaffold protein;
GN  Tamalin;
OS  10116;
SL  Nucleus Position: SL-0198;
SL  Comments: Cytoplasm, perinuclear region {ECO:0000269|PubMed:11850456}. Cell membrane {ECO:0000269|PubMed:11850456}; Peripheral membrane protein {ECO:0000269|PubMed:11850456}; Cytoplasmic side {ECO:0000269|PubMed:11850456}. Postsynaptic cell membrane {ECO:0000269|PubMed:11850456}.
DR  UNIPROT: Q8R4T5;
DR  PDB: 2EGK;
DR  PDB: 2EGN;
DR  PDB: 2EGO;
DR  Pfam: PF00595;
DR  PROSITE: PS50106;
DE  Function: Plays a role in intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses. {ECO:0000269|PubMed:11850456}.
DE  Reference Proteome: Yes;
DE  Interaction: P63035; IntAct: EBI-8600171; Score: 0.37
DE  Interaction: Q91Y79; IntAct: EBI-8600241; Score: 0.37
DE  Interaction: P14314; IntAct: EBI-8600313; Score: 0.37
DE  Interaction: O94868; IntAct: EBI-8600330; Score: 0.37
DE  Interaction: O15062; IntAct: EBI-8600386; Score: 0.37
DE  Interaction: Q8R515; IntAct: EBI-8600369; Score: 0.37
DE  Interaction: P97838; IntAct: EBI-8600437; Score: 0.51
DE  Interaction: Q9Y592; IntAct: EBI-8600403; Score: 0.37
DE  Interaction: P11274; IntAct: EBI-8600478; Score: 0.37
DE  Interaction: O88573; IntAct: EBI-8600550; Score: 0.37
DE  Interaction: O35431; IntAct: EBI-8600652; Score: 0.52
DE  Interaction: O88382; IntAct: EBI-8600638; Score: 0.70
DE  Interaction: P31016; IntAct: EBI-8600666; Score: 0.52
DE  Interaction: P97836; IntAct: EBI-8600894; Score: 0.40
DE  Interaction: Q62915; IntAct: EBI-8600971; Score: 0.40
DE  Interaction: Q8R4T5; IntAct: EBI-8600781; Score: 0.67
DE  Interaction: P31424; IntAct: EBI-7361910; Score: 0.63
GO  GO:0070161;
GO  GO:0098978;
GO  GO:0048471;
GO  GO:0005886;
GO  GO:0014069;
GO  GO:0045211;
GO  GO:0098685;
GO  GO:0042802;
GO  GO:0030165;
GO  GO:0031267;
GO  GO:0008104;
GO  GO:0099152;
GO  GO:0007165;
TP  Membrane Topology: Peripheral; Source: UniProt - Experimental Evidence {ECO:0000269|PubMed:11850456};
SQ  MTLRRLRKLQQKEEATAAPDLAGRAPDSEAARAAPTPSGPPAAAAPPGAPGDELYAALEDYHPAELYRALAVSGGTLPRR
SQ  KGSGFRWKNFTQSPEQQRKVLTLEKGDNQTFGFEIQTYGLHHREEQRVEMVTFVCRVHESSPAQLAGLTPGDTIASVNGL
SQ  NVEGIRHREIVDIIKASGNVLRLETLYGTSIRKAELEARLQYLKQTLYEKWGEYRSLMVQEQRLVHGLVVKDPSIYDTLE
SQ  SVRSCLYGAGLLPGSLPFGPLLAAPGGARGGSRRAKGDTDDAVYHTCFFGGAEPQALPPPPPPARAPGPGSAETPASVLC
SQ  PAPRATLSRSASVRCAGPGGGGGGGAPGALWTEAREQALCGAGLRKTKYRSFRRRLLKFIPGLNRSLEEEESQL
//