ID  Q90987;
PN  Stathmin-2;
GN  STMN2;
OS  9031;
SL  Nucleus Position: SL-0198;
SL  Comments: Cytoplasm {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Cell projection, growth cone {ECO:0000250}. Membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cell projection, axon {ECO:0000250}. Cell projection, lamellipodium {ECO:0000250}. Note=Associated with punctate structures in the perinuclear cytoplasm, axons, and growth cones of developing neurons. SCG10 exists in both soluble and membrane- bound forms (By similarity). {ECO:0000250}.
DR  UNIPROT: Q90987;
DR  Pfam: PF00836;
DR  PROSITE: PS00563;
DR  PROSITE: PS01041;
DR  PROSITE: PS51663;
DE  Function: Is a key regulator of neurite extension through regulation of microtubule instabilily. {ECO:0000250}.
DE  Reference Proteome: Yes;
GO  GO:0005737;
GO  GO:0030426;
GO  GO:0030027;
GO  GO:0016020;
GO  GO:0043005;
GO  GO:0043025;
GO  GO:0048471;
GO  GO:0048306;
GO  GO:0015631;
GO  GO:1990090;
GO  GO:0007019;
GO  GO:0007026;
GO  GO:0031115;
GO  GO:0010977;
GO  GO:0031175;
GO  GO:0031117;
GO  GO:0010976;
GO  GO:0031110;
TP  Membrane Topology: Peripheral; Source: UniProt - Curator Inference {ECO:0000305};
SQ  MAKTAMAYKEKMKELSMLSLICSCFYPEPRNMNIYKYDDMEVKQINKRASGQAFELILKPPSPVSEAPRTLASPKKKELS
SQ  LEEIQKKLEAAEERRKSQEAQVLKHLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQIKENREANLAALIERLQEK
SQ  ERHAAEVRRNKELQVELSG
//