ID  Q90ZZ6;
PN  Nanos homolog 1;
GN  nanos1;
OS  8364;
SL  Nucleus Position: SL-0198;
SL  Comments: Cytoplasm {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Note=During early cleavage and blastula stages found close to the cell periphery in a germ plasm-like pattern. From gastrula stage on, detected predominantly in a perinuclear region (By similarity). {ECO:0000250}.
DR  UNIPROT: Q90ZZ6;
DR  UNIPROT: B7ZTT7;
DR  Pfam: PF05741;
DR  PROSITE: PS51522;
DE  Function: Acts as a translational repressor. Can mediate repression affecting different steps in the translation process: cap-driven, IRES- driven, polyadenylated RNAs or nonpolyadenylated RNAs. Essential for the development of primordial germ cells (PGCs) by ensuring their proper migration and survival (By similarity). {ECO:0000250}.
DE  Reference Proteome: Yes;
GO  GO:0005737;
GO  GO:0060293;
GO  GO:0048471;
GO  GO:0003729;
GO  GO:0030371;
GO  GO:0008270;
GO  GO:0007281;
GO  GO:0008354;
GO  GO:0017148;
GO  GO:0048477;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MDGGLCFNSWSDYLGLSSLISRGLQPREGGESPRPRWKASSPTPAEPLPSKAAEAHGHKGCGFCRSNREAQSLYSSHRLR
SQ  APDGRVLCPVLRGYTCPLCGANGDWAHTMRYCPLRHFLRHPHSPRDGQ
//