ID  Q91ZF2;
PN  Cathepsin 7;
GN  Cts7;
OS  10090;
SL  Nucleus Position: SL-0198;
SL  Comments: Endosome {ECO:0000269|PubMed:18776147, ECO:0000305}. Lysosome {ECO:0000269|PubMed:18776147, ECO:0000305}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:18776147}. Golgi apparatus {ECO:0000269|PubMed:18776147, ECO:0000305}. Nucleus {ECO:0000269|PubMed:18776147}. Secreted, extracellular space {ECO:0000269|PubMed:18776147}.
DR  UNIPROT: Q91ZF2;
DR  UNIPROT: Q9JI84;
DR  Pfam: PF08246;
DR  Pfam: PF00112;
DR  PROSITE: PS00139;
DR  PROSITE: PS00639;
DE  Function: Involved in trophoblast cell proliferation and differentiation probably by affecting mitotic cell cycle progression. Proteolytic activity and nuclear localization are essential for its role in cell cycle progression. {ECO:0000269|PubMed:18776147}.
DE  Reference Proteome: Yes;
GO  GO:0005768;
GO  GO:0005576;
GO  GO:0005615;
GO  GO:0005794;
GO  GO:0005764;
GO  GO:0005634;
GO  GO:0048471;
GO  GO:0004197;
GO  GO:0008233;
GO  GO:0051301;
GO  GO:0006955;
GO  GO:0000278;
GO  GO:0045930;
GO  GO:0006508;
GO  GO:0051603;
GO  GO:0060707;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MTPTVFLSILCLGVALAAPAPDYNLDAEWEEWKRSNDRTYSPEEEKQRRAVWEGNVKWIKQHIMENGLWMNNFTIEMNEF
SQ  GDMTGEEMKMLTESSSYPLRNGKHIQKRNPKIPPTLDWRKEGYVTPVRRQGSCGACWAFSVTACIEGQLFKKTGKLIPLS
SQ  VQNLMDCSVSYGTKGCDGGRPYDAFQYVKNNGGLEAEATYPYEAKAKHCRYRPERSVVKVNRFFVVPRNEEALLQALVTH
SQ  GPIAVAIDGSHASFHSYRGGIYHEPKCRKDTLDHGLLLVGYGYEGHESENRKYWLLKNSHGERWGENGYMKLPRGQNNYC
SQ  GIASYAMYPAL
//