ID  Q92832;
PN  Protein kinase C-binding protein NELL1;
GN  NELL1;
OS  9606;
SL  Nucleus Position: SL-0178;
SL  Comments: Cytoplasm {ECO:0000269|PubMed:21723284}. Nucleus envelope {ECO:0000269|PubMed:21723284}. Secreted {ECO:0000250}. Note=Colocalizes with ATRAID on the nuclear envelope and the perinuclear region.
DR  UNIPROT: Q92832;
DR  UNIPROT: B2CKC1;
DR  UNIPROT: Q4VB90;
DR  UNIPROT: Q4VB91;
DR  UNIPROT: Q6NSY8;
DR  UNIPROT: Q9Y472;
DR  PDB: 6POL;
DR  Pfam: PF12947;
DR  Pfam: PF07645;
DR  Pfam: PF00093;
DR  PROSITE: PS00010;
DR  PROSITE: PS00022;
DR  PROSITE: PS01186;
DR  PROSITE: PS50026;
DR  PROSITE: PS01187;
DR  PROSITE: PS01208;
DR  PROSITE: PS50184;
DR  OMIM: 602319;
DR  DisGeNET: 4745;
DE  Function: Plays a role in the control of cell growth and differentiation. Promotes osteoblast cell differentiation and terminal mineralization. {ECO:0000269|PubMed:21723284}.
DE  Reference Proteome: Yes;
DE  Interaction: O75147; IntAct: EBI-21661122; Score: 0.35
DE  Interaction: P00533; IntAct: EBI-8769968; Score: 0.35
DE  Interaction: P54259; IntAct: EBI-950854; Score: 0.00
DE  Interaction: Q6UW56; IntAct: EBI-7001256; Score: 0.61
DE  Interaction: Q5VTD9; IntAct: EBI-953008; Score: 0.00
DE  Interaction: O15265; IntAct: EBI-3866546; Score: 0.37
DE  Interaction: O00555; IntAct: EBI-3867376; Score: 0.37
DE  Interaction: P23588; IntAct: EBI-7001271; Score: 0.40
DE  Interaction: P68104; IntAct: EBI-7001286; Score: 0.40
DE  Interaction: O60841; IntAct: EBI-7001316; Score: 0.40
DE  Interaction: Q6IN85; IntAct: EBI-7001346; Score: 0.40
DE  Interaction: P19174; IntAct: EBI-7001331; Score: 0.40
DE  Interaction: Q9BSC4; IntAct: EBI-7001400; Score: 0.40
DE  Interaction: Q9NWH9; IntAct: EBI-7001361; Score: 0.40
DE  Interaction: Q08945; IntAct: EBI-7001415; Score: 0.40
DE  Interaction: Q5QJE6; IntAct: EBI-7001430; Score: 0.40
DE  Interaction: Q0ZGT2; IntAct: EBI-7001445; Score: 0.40
DE  Interaction: Q9WMX2; IntAct: EBI-9081118; Score: 0.37
DE  Interaction: Q6FHY5; IntAct: EBI-24468498; Score: 0.56
DE  Interaction: Q8NI29; IntAct: EBI-21661122; Score: 0.35
DE  Interaction: Q9UHF1; IntAct: EBI-21661122; Score: 0.35
DE  Interaction: Q9H8K7; IntAct: EBI-21661122; Score: 0.35
DE  Interaction: Q9C0F1; IntAct: EBI-21661122; Score: 0.35
DE  Interaction: Q9BXX0; IntAct: EBI-21661122; Score: 0.35
DE  Interaction: Q96S44; IntAct: EBI-21661122; Score: 0.35
DE  Interaction: Q96GJ1; IntAct: EBI-21661122; Score: 0.35
DE  Interaction: Q92626; IntAct: EBI-21661122; Score: 0.35
DE  Interaction: Q8N2S1; IntAct: EBI-21661122; Score: 0.35
DE  Interaction: Q6IPR3; IntAct: EBI-21661122; Score: 0.35
DE  Interaction: Q5BLP8; IntAct: EBI-21661122; Score: 0.35
DE  Interaction: Q3ZCT1; IntAct: EBI-21661122; Score: 0.35
DE  Interaction: Q01813; IntAct: EBI-21661122; Score: 0.35
DE  Interaction: P55268; IntAct: EBI-21661122; Score: 0.35
DE  Interaction: P35625; IntAct: EBI-21661122; Score: 0.35
DE  Interaction: P23142; IntAct: EBI-21661122; Score: 0.35
DE  Interaction: O14757; IntAct: EBI-21661122; Score: 0.35
DE  Interaction: O00411; IntAct: EBI-21661122; Score: 0.35
DE  Interaction: O00339; IntAct: EBI-21661122; Score: 0.35
DE  Interaction: P14404; IntAct: EBI-21026252; Score: 0.35
DE  Interaction: P0DOF2; IntAct: EBI-25603126; Score: 0.35
DE  Interaction: P49639; IntAct: EBI-26512606; Score: 0.37
DE  Interaction: Q9UIS9; IntAct: EBI-26512884; Score: 0.37
DE  Interaction: Q7Z417; IntAct: EBI-26513515; Score: 0.37
GO  GO:0005737;
GO  GO:0005576;
GO  GO:0005635;
GO  GO:0048471;
GO  GO:0005509;
GO  GO:0008201;
GO  GO:0005080;
GO  GO:0030154;
GO  GO:0033689;
GO  GO:0042177;
GO  GO:0007399;
GO  GO:0030501;
GO  GO:0045669;
GO  GO:0010468;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MPMDLILVVWFCVCTARTVVGFGMDPDLQMDIVTELDLVNTTLGVAQVSGMHNASKAFLFQDIEREIHAAPHVSEKLIQL
SQ  FRNKSEFTILATVQQKPSTSGVILSIRELEHSYFELESSGLRDEIRYHYIHNGKPRTEALPYRMADGQWHKVALSVSASH
SQ  LLLHVDCNRIYERVIDPPDTNLPPGINLWLGQRNQKHGLFKGIIQDGKIIFMPNGYITQCPNLNHTCPTCSDFLSLVQGI
SQ  MDLQELLAKMTAKLNYAETRLSQLENCHCEKTCQVSGLLYRDQDSWVDGDHCRNCTCKSGAVECRRMSCPPLNCSPDSLP
SQ  VHIAGQCCKVCRPKCIYGGKVLAEGQRILTKSCRECRGGVLVKITEMCPPLNCSEKDHILPENQCCRVCRGHNFCAEGPK
SQ  CGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDEC
SQ  GSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCEEGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECSEGIIEC
SQ  HNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSGPSCSGDCPHEGGL
SQ  KHNGQVWTLKEDRCSVCSCKDGKIFCRRTACDCQNPSADLFCCPECDTRVTSQCLDQNGHKLYRSGDNWTHSCQQCRCLE
SQ  GEVDCWPLTCPNLSCEYTAILEGECCPRCVSDPCLADNITYDIRKTCLDSYGVSRLSGSVWTMAGSPCTTCKCKNGRVCC
SQ  SVDFECLQNN
//