ID  Q94AV5;
PN  WPP domain-interacting protein 3;
GN  WIP3;
OS  3702;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0182;
SL  Comments: Nucleus envelope {ECO:0000269|PubMed:17600715, ECO:0000269|PubMed:22270916}. Nucleus membrane {ECO:0000269|PubMed:17600715}; Single-pass membrane protein {ECO:0000269|PubMed:17600715}; Cytoplasmic side {ECO:0000269|PubMed:17600715}.
DR  UNIPROT: Q94AV5;
DR  UNIPROT: Q9LTT2;
DE  Function: Mediates and enhances the nuclear envelope docking of RANGAP proteins mediated by WIT1 and WIT2 in the undifferentiated cells of root tips (PubMed:17600715). As component of the SUN-WIP-WIT2-KAKU1 complex, mediates the transfer of cytoplasmic forces to the nuclear envelope (NE), leading to nuclear shape changes (PubMed:25759303). {ECO:0000269|PubMed:17600715, ECO:0000269|PubMed:25759303}.
DE  Reference Proteome: Yes;
DE  Interaction: Q8GXA4; IntAct: EBI-1779708; Score: 0.37
DE  Interaction: Q9LE82; IntAct: EBI-1779492; Score: 0.49
DE  Interaction: Q9FMH6; IntAct: EBI-1779613; Score: 0.37
DE  Interaction: Q9C500; IntAct: EBI-1779636; Score: 0.37
GO  GO:0016021;
GO  GO:0005635;
GO  GO:0031965;
GO  GO:0006997;
TP  Membrane Topology: Transmembrane; Source: UniProt - Sequence Analysis {ECO:0000255};
SQ  MNESVPDSVEDNGNSVPANGLLVLPDNDHEEGGVGSPQRSNSVESPGGSVHSTRKGFGLKKWRRIKRDGPVRDEAAPVDD
SQ  GSKLLKRGLAGLVNPPSKHVEFSSVEARQSSEGSVGSVNMVHHPGVANGFSPDIGCMFAVGQAFEKSEEHSGNTIGGKNV
SQ  VGGKVVSGSQEKLWSDTIKRASEERGDIEKEKPCSSLDSDLRSSDFVFSTGSVSVGNHGEKDERLTMNYIGGFSNEGQVK
SQ  EEVQTYSRSENGNKEDDGESKKNNNHWADKDALADSIRSFAVLQEVLWKEVQSFQELGKESVLLHSNTDELSSDQPSHQN
SQ  CKEDNSTSSGSKALILKEKVKLLEHKLEEARAALEAKEARIQELENSKIESELECIFQRKIETEIEHLMLTRSLSSLQVL
SQ  QETKKLHSLKEDPVSNRGNILGKTCKLGFYILTQLILLVSILRFLVLQFSPASRLVIPT
//