ID  Q96321;
PN  Importin subunit alpha-1;
GN  IMPA1;
OS  3702;
SL  Nucleus Position: SL-0178;
SL  Comments: Nucleus envelope {ECO:0000269|PubMed:8776900}.
DR  UNIPROT: Q96321;
DR  UNIPROT: O49599;
DR  UNIPROT: O81520;
DR  UNIPROT: Q940R6;
DR  UNIPROT: Q9C841;
DR  UNIPROT: Q9ZRI5;
DR  Pfam: PF00514;
DR  Pfam: PF16186;
DR  Pfam: PF01749;
DR  PROSITE: PS50176;
DR  PROSITE: PS51214;
DE  Function: Binds to conventional NLS motifs with high affinity in the absence of an importin beta subunit. Mediates nuclear protein import across the nuclear envelope in vitro in the absence of exogenously added importin beta subunit (PubMed:10428841). Acts as cellular receptor for the nuclear import of the virD2 protein of Agrobacterium, but is not essential for Agrobacterium-mediated root transformation (PubMed:18836040). {ECO:0000269|PubMed:10428841, ECO:0000269|PubMed:18836040}.
DE  Reference Proteome: Yes;
DE  Interaction: Q94CL9; IntAct: EBI-2131462; Score: 0.00
DE  Interaction: Q9FNY0; IntAct: EBI-2651578; Score: 0.00
DE  Interaction: Q9SCR2; IntAct: EBI-2651636; Score: 0.00
DE  Interaction: F4KAB8; IntAct: EBI-2651692; Score: 0.00
DE  Interaction: Q9SGE2; IntAct: EBI-2651779; Score: 0.00
DE  Interaction: Q29Q81; IntAct: EBI-2651808; Score: 0.00
DE  Interaction: Q9SAD3; IntAct: EBI-2651816; Score: 0.00
DE  Interaction: Q8GX29; IntAct: EBI-4496832; Score: 0.37
DE  Interaction: A2RVU4; IntAct: EBI-4510528; Score: 0.37
DE  Interaction: O22286; IntAct: EBI-4510536; Score: 0.37
DE  Interaction: O22768; IntAct: EBI-4510544; Score: 0.37
DE  Interaction: O22798; IntAct: EBI-4510552; Score: 0.37
DE  Interaction: O64645; IntAct: EBI-4510560; Score: 0.37
DE  Interaction: O65282; IntAct: EBI-4510568; Score: 0.37
DE  Interaction: O65555; IntAct: EBI-4510576; Score: 0.37
DE  Interaction: O80837; IntAct: EBI-4510584; Score: 0.37
DE  Interaction: O81439; IntAct: EBI-4510592; Score: 0.37
DE  Interaction: P49678; IntAct: EBI-4510600; Score: 0.37
DE  Interaction: Q00218; IntAct: EBI-4510608; Score: 0.37
DE  Interaction: Q05466; IntAct: EBI-4510616; Score: 0.37
DE  Interaction: Q058P7; IntAct: EBI-4510624; Score: 0.37
DE  Interaction: Q2VWA2; IntAct: EBI-4510632; Score: 0.37
DE  Interaction: Q6NQ78; IntAct: EBI-4510640; Score: 0.37
DE  Interaction: Q8H1S2; IntAct: EBI-4510648; Score: 0.37
DE  Interaction: Q0WLB5; IntAct: EBI-4510656; Score: 0.37
DE  Interaction: Q8L866; IntAct: EBI-4510664; Score: 0.37
DE  Interaction: Q8LPR2; IntAct: EBI-4510672; Score: 0.37
DE  Interaction: Q8RWF8; IntAct: EBI-4510680; Score: 0.37
DE  Interaction: Q8RWK8; IntAct: EBI-4510688; Score: 0.37
DE  Interaction: Q8VY49; IntAct: EBI-4510696; Score: 0.37
DE  Interaction: Q8VZE5; IntAct: EBI-4510704; Score: 0.37
DE  Interaction: Q8VZL7; IntAct: EBI-4510712; Score: 0.37
DE  Interaction: Q93ZB7; IntAct: EBI-4510720; Score: 0.37
DE  Interaction: Q940I0; IntAct: EBI-4510728; Score: 0.37
DE  Interaction: Q94AF2; IntAct: EBI-4510736; Score: 0.37
DE  Interaction: Q94BU9; IntAct: EBI-4510744; Score: 0.37
DE  Interaction: Q94JQ3; IntAct: EBI-4510752; Score: 0.37
DE  Interaction: Q96292; IntAct: EBI-4510760; Score: 0.37
DE  Interaction: Q9ASW4; IntAct: EBI-4510768; Score: 0.37
DE  Interaction: Q9FKD7; IntAct: EBI-4510776; Score: 0.37
DE  Interaction: Q9FNN2; IntAct: EBI-4510784; Score: 0.37
DE  Interaction: Q9LU63; IntAct: EBI-4510792; Score: 0.37
DE  Interaction: Q9LUK6; IntAct: EBI-4510800; Score: 0.37
DE  Interaction: Q9STS3; IntAct: EBI-4510808; Score: 0.37
DE  Interaction: Q9SZZ4; IntAct: EBI-4510816; Score: 0.37
DE  Interaction: Q9LUA3; IntAct: EBI-4521560; Score: 0.37
DE  Interaction: Q9SIC8; IntAct: EBI-4527472; Score: 0.37
DE  Interaction: F8RP38; IntAct: EBI-6368593; Score: 0.58
DE  Interaction: O22467; IntAct: EBI-6673033; Score: 0.35
GO  GO:0005737;
GO  GO:0005635;
GO  GO:0005730;
GO  GO:0005634;
GO  GO:0009505;
GO  GO:0061608;
GO  GO:0008139;
GO  GO:0006607;
GO  GO:0006606;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MSLRPNAKTEVRRNRYKVAVDAEEGRRRREDNMVEIRKSKREESLMKKRREGMQALQGFPSASAASVDKKLDSLKDMVAG
SQ  VWSDDPALQLESTTQFRKLLSIERSPPIEEVISAGVVPRFVEFLKKEDYPAIQFEAAWALTNIASGTSDHTKVVIDHNAV
SQ  PIFVQLLASPSDDVREQAVWALGNVAGDSPRCRDLVLGCGALLPLLNQLNEHAKLSMLRNATWTLSNFCRGKPQPHFDQV
SQ  KPALPALERLIHSDDEEVLTDACWALSYLSDGTNDKIQTVIQAGVVPKLVELLLHHSPSVLIPALRTVGNIVTGDDIQTQ
SQ  CVINSGALPCLANLLTQNHKKSIKKEACWTISNITAGNKDQIQTVVEANLISPLVSLLQNAEFDIKKEAAWAISNATSGG
SQ  SHDQIKYLVEQGCIKPLCDLLVCPDPRIITVCLEGLENILKVGEAEKNLGHTGDMNYYAQLIDDAEGLEKIENLQSHDNN
SQ  EIYEKAVKILETYWLEEEDDETQQPPGVDGSQAGFQFGGNQAPVPSGGFNFS
//