ID  Q96B42;
PN  Transmembrane protein 18;
GN  TMEM18;
OS  9606;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0182;
SL  Comments: Cytoplasm {ECO:0000269|PubMed:18559506, ECO:0000269|PubMed:21980424}. Nucleus membrane {ECO:0000269|PubMed:18559506, ECO:0000269|PubMed:21980424}; Multi-pass membrane protein {ECO:0000255}.
DR  UNIPROT: Q96B42;
DR  UNIPROT: D6W4X9;
DR  UNIPROT: Q8N5H2;
DR  UNIPROT: Q9NTH3;
DR  Pfam: PF14770;
DR  OMIM: 613220;
DR  DisGeNET: 129787;
DE  Function: Transcription repressor. Sequence-specific ssDNA and dsDNA binding protein, with preference for GCT end CTG repeats. Cell migration modulator which enhances the glioma-specific migration ability of neural stem cells (NSC) and neural precursor cells (NPC). {ECO:0000269|PubMed:18559506, ECO:0000269|PubMed:21980424}.
DE  Reference Proteome: Yes;
DE  Interaction: Q9H6H4; IntAct: EBI-24677832; Score: 0.56
DE  Interaction: Q86VR2; IntAct: EBI-25283341; Score: 0.56
GO  GO:0005737;
GO  GO:0016021;
GO  GO:0031965;
GO  GO:0003677;
GO  GO:0016477;
TP  Membrane Topology: Transmembrane; Source: UniProt - Sequence Analysis {ECO:0000255};
SQ  MPSAFSVSSFPVSIPAVLTQTDWTEPWLMGLATFHALCVLLTCLSSRSYRLQIGHFLCLVILVYCAEYINEAAAMNWRLF
SQ  SKYQYFDSRGMFISIVFSAPLLVNAMIIVVMWVWKTLNVMTDLKNAQERRKEKKRRRKED
//