ID  Q96HJ5;
PN  Membrane-spanning 4-domains subfamily A member 3;
GN  MS4A3;
OS  9606;
SL  Nucleus Position: SL-0198;
SL  Comments: Endomembrane system {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Note=Located in the perinuclear area.
DR  UNIPROT: Q96HJ5;
DR  UNIPROT: A8MTP8;
DR  UNIPROT: Q8NHW2;
DR  Pfam: PF04103;
DR  OMIM: 606498;
DR  DisGeNET: 932;
DE  Function: Hematopoietic modulator for the G1-S cell cycle transition. Modulates the level of phosphorylation of cyclin-dependent kinase 2 (CDK2) through its direct binding to cyclin-dependent kinase inhibitor 3 (CDKN3/KAP). {ECO:0000269|PubMed:11781350}.
DE  Reference Proteome: Yes;
DE  Interaction: Q01628; IntAct: EBI-24801917; Score: 0.56
DE  Interaction: Q8IY26; IntAct: EBI-24595440; Score: 0.56
DE  Interaction: Q9UNK0; IntAct: EBI-24517101; Score: 0.56
DE  Interaction: Q9NRQ5; IntAct: EBI-24520672; Score: 0.56
DE  Interaction: A2RU14; IntAct: EBI-24532611; Score: 0.56
DE  Interaction: Q9Y267; IntAct: EBI-24607353; Score: 0.60
DE  Interaction: P55061; IntAct: EBI-24609547; Score: 0.56
DE  Interaction: Q9Y6I9; IntAct: EBI-24610634; Score: 0.60
DE  Interaction: Q16617; IntAct: EBI-24611877; Score: 0.56
DE  Interaction: P24593; IntAct: EBI-24612958; Score: 0.56
DE  Interaction: Q8WVX3; IntAct: EBI-24614489; Score: 0.56
DE  Interaction: Q9P0B6; IntAct: EBI-24619069; Score: 0.56
DE  Interaction: Q9UKR5; IntAct: EBI-24620954; Score: 0.56
DE  Interaction: P60201; IntAct: EBI-24623326; Score: 0.56
DE  Interaction: Q99437; IntAct: EBI-24639063; Score: 0.56
DE  Interaction: Q15848; IntAct: EBI-24689161; Score: 0.56
DE  Interaction: Q6ZP80; IntAct: EBI-24538049; Score: 0.56
DE  Interaction: O95832; IntAct: EBI-24536228; Score: 0.56
DE  Interaction: Q8N0U8; IntAct: EBI-24537215; Score: 0.56
DE  Interaction: Q96CE8; IntAct: EBI-24540310; Score: 0.56
DE  Interaction: Q6UX40; IntAct: EBI-24543702; Score: 0.56
DE  Interaction: Q8WW34; IntAct: EBI-24544415; Score: 0.56
DE  Interaction: Q12983; IntAct: EBI-24546891; Score: 0.56
DE  Interaction: P19397; IntAct: EBI-24547321; Score: 0.56
DE  Interaction: Q5J8X5; IntAct: EBI-24548625; Score: 0.56
DE  Interaction: Q9NV12; IntAct: EBI-24571283; Score: 0.56
DE  Interaction: O95159; IntAct: EBI-24576289; Score: 0.56
DE  Interaction: P52803; IntAct: EBI-24577069; Score: 0.56
DE  Interaction: Q96EC8; IntAct: EBI-24578834; Score: 0.56
DE  Interaction: Q96IW7; IntAct: EBI-24578812; Score: 0.56
DE  Interaction: Q9BZL3; IntAct: EBI-24596021; Score: 0.56
DE  Interaction: P56747; IntAct: EBI-24596210; Score: 0.56
DE  Interaction: O43765; IntAct: EBI-24596868; Score: 0.56
DE  Interaction: Q9NY91; IntAct: EBI-24602190; Score: 0.56
DE  Interaction: P54852; IntAct: EBI-24639148; Score: 0.56
DE  Interaction: O95393; IntAct: EBI-24800071; Score: 0.56
DE  Interaction: P21854; IntAct: EBI-24807056; Score: 0.56
GO  GO:0016021;
GO  GO:0048471;
GO  GO:0005886;
GO  GO:0035579;
GO  GO:0007166;
GO  GO:0051726;
TP  Membrane Topology: Transmembrane; Source: UniProt - Sequence Analysis {ECO:0000255};
SQ  MASHEVDNAELGSASAHGTPGSEAGPEELNTSVYQPIDGSPDYQKAKLQVLGAIQILNAAMILALGVFLGSLQYPYHFQK
SQ  HFFFFTFYTGYPIWGAVFFCSSGTLSVVAGIKPTRTWIQNSFGMNIASATIALVGTAFLSLNIAVNIQSLRSCHSSSESP
SQ  DLCNYMGSISNGMVSLLLILTLLELCVTISTIAMWCNANCCNSREEISSPPNSV
//