ID  Q9BTX1;
PN  Nucleoporin NDC1;
GN  NDC1;
OS  9606;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0182;
SL  Nucleus Position: SL-0185;
SL  Comments: Nucleus, nuclear pore complex. Nucleus membrane; Multi-pass membrane protein. Note=Central core structure of the nuclear pore complex.
DR  UNIPROT: Q9BTX1;
DR  UNIPROT: B4DHA3;
DR  UNIPROT: B4DQQ5;
DR  UNIPROT: G3XA81;
DR  UNIPROT: Q8NB76;
DR  UNIPROT: Q9H9T6;
DR  UNIPROT: Q9NSG3;
DR  UNIPROT: Q9NSG4;
DR  UNIPROT: Q9NVZ7;
DR  Pfam: PF09531;
DR  OMIM: 610115;
DR  DisGeNET: 55706;
DE  Function: Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane. {ECO:0000269|PubMed:16600873, ECO:0000269|PubMed:16702233}.
DE  Reference Proteome: Yes;
DE  Interaction: A0A142I5B9; IntAct: EBI-20626314; Score: 0.35
DE  Interaction: O95476; IntAct: EBI-27115722; Score: 0.27
DE  Interaction: P49790; IntAct: EBI-11076796; Score: 0.35
DE  Interaction: P57740; IntAct: EBI-11160436; Score: 0.35
DE  Interaction: P63279; IntAct: EBI-11105225; Score: 0.35
DE  Interaction: Q14974; IntAct: EBI-11115566; Score: 0.35
DE  Interaction: Q6PFD9; IntAct: EBI-10994876; Score: 0.35
DE  Interaction: Q8BH74; IntAct: EBI-10997196; Score: 0.35
DE  Interaction: Q8VCB1; IntAct: EBI-2560113; Score: 0.40
DE  Interaction: Q8WTR4; IntAct: EBI-21566764; Score: 0.35
DE  Interaction: Q96EE3; IntAct: EBI-11086798; Score: 0.35
DE  Interaction: Q99P88; IntAct: EBI-10997466; Score: 0.35
DE  Interaction: Q8IYM1; IntAct: EBI-10819461; Score: 0.37
DE  Interaction: Q9ERU9; IntAct: EBI-10999306; Score: 0.35
DE  Interaction: P36895; IntAct: EBI-11008521; Score: 0.35
DE  Interaction: Q8VE37; IntAct: EBI-11043815; Score: 0.35
DE  Interaction: P63280; IntAct: EBI-11044140; Score: 0.35
DE  Interaction: Q9BVL2; IntAct: EBI-11077390; Score: 0.35
DE  Interaction: Q6NUS6; IntAct: EBI-11368748; Score: 0.27
DE  Interaction: Q86X19; IntAct: EBI-11372615; Score: 0.27
DE  Interaction: Q96GX1; IntAct: EBI-11375285; Score: 0.27
DE  Interaction: Q9P0N5; IntAct: EBI-11378021; Score: 0.27
DE  Interaction: Q86UK5; IntAct: EBI-11389870; Score: 0.27
DE  Interaction: Q8IWL3; IntAct: EBI-13943458; Score: 0.35
DE  Interaction: O00322; IntAct: EBI-21504674; Score: 0.35
DE  Interaction: P30825; IntAct: EBI-21505748; Score: 0.35
DE  Interaction: Q86UE6; IntAct: EBI-21507777; Score: 0.35
DE  Interaction: Q9H8X2; IntAct: EBI-21509881; Score: 0.35
DE  Interaction: Q9Y282; IntAct: EBI-21510632; Score: 0.35
DE  Interaction: P16444; IntAct: EBI-21514808; Score: 0.35
DE  Interaction: Q16581; IntAct: EBI-21515265; Score: 0.35
DE  Interaction: Q6P5W5; IntAct: EBI-21515976; Score: 0.35
DE  Interaction: P35414; IntAct: EBI-21559824; Score: 0.35
DE  Interaction: Q8WWF5; IntAct: EBI-21589535; Score: 0.35
DE  Interaction: P62079; IntAct: EBI-21619035; Score: 0.35
DE  Interaction: Q6UWB1; IntAct: EBI-21703330; Score: 0.35
DE  Interaction: P08754; IntAct: EBI-21709056; Score: 0.35
DE  Interaction: P28908; IntAct: EBI-21750180; Score: 0.35
DE  Interaction: Q9UQC9; IntAct: EBI-21899358; Score: 0.40
DE  Interaction: P27824; IntAct: EBI-16788621; Score: 0.27
DE  Interaction: E7ELX2; IntAct: EBI-20625922; Score: 0.35
DE  Interaction: A2A935; IntAct: EBI-21022882; Score: 0.35
DE  Interaction: P14404; IntAct: EBI-21026252; Score: 0.35
DE  Interaction: F5H1C8; IntAct: EBI-21264930; Score: 0.35
DE  Interaction: Q9H1C4; IntAct: EBI-21266770; Score: 0.35
DE  Interaction: Q15077; IntAct: EBI-21272198; Score: 0.35
DE  Interaction: P0DTD8; IntAct: EBI-25687199; Score: 0.35
DE  Interaction: Q2TAZ0; IntAct: EBI-26443127; Score: 0.35
DE  Interaction: P01116; IntAct: EBI-27041844; Score: 0.27
DE  Interaction: P01111; IntAct: EBI-27042293; Score: 0.27
DE  Interaction: A0A0F6B5H5; IntAct: EBI-27033770; Score: 0.35
DE  Interaction: A0A0H3NB75; IntAct: EBI-27055718; Score: 0.42
DE  Interaction: Q9UM73; IntAct: EBI-32719830; Score: 0.27
DE  Interaction: P29322; IntAct: EBI-32721175; Score: 0.27
DE  Interaction: P08069; IntAct: EBI-32722947; Score: 0.27
DE  Interaction: P06213; IntAct: EBI-32723092; Score: 0.27
DE  Interaction: O15146; IntAct: EBI-32724025; Score: 0.27
DE  Interaction: Q16288; IntAct: EBI-32724526; Score: 0.27
GO  GO:0015629;
GO  GO:0005737;
GO  GO:0016021;
GO  GO:0016020;
GO  GO:0005635;
GO  GO:0031965;
GO  GO:0005643;
GO  GO:0070762;
GO  GO:0005886;
GO  GO:0030674;
GO  GO:0017056;
GO  GO:0007129;
GO  GO:0051028;
GO  GO:0051292;
GO  GO:0051664;
GO  GO:0006999;
GO  GO:0006913;
GO  GO:0015031;
GO  GO:0007283;
TP  Membrane Topology: Transmembrane; Source: UniProt - Sequence Analysis {ECO:0000255};
SQ  MATAVSRPCAGRSRDILWRVLGWRIVASIVWSVLFLPICTTVFIIFSRIDLFHPIQWLSDSFSDLYSSYVIFYFLLLSVV
SQ  IIIISIFNVEFYAVVPSIPCSRLALIGKIIHPQQLMHSFIHAAMGMVMAWCAAVITQGQYSFLVVPCTGTNSFGSPAAQT
SQ  CLNEYHLFFLLTGAFMGYSYSLLYFVNNMNYLPFPIIQQYKFLRFRRSLLLLVKHSCVESLFLVRNFCILYYFLGYIPKA
SQ  WISTAMNLHIDEQVHRPLDTVSGLLNLSLLYHVWLCGVFLLTTWYVSWILFKIYATEAHVFPVQPPFAEGSDECLPKVLN
SQ  SNPPPIIKYLALQDLMLLSQYSPSRRQEVFSLSQPGGHPHNWTAISRECLNLLNGMTQKLILYQEAAATNGRVSSSYPVE
SQ  PKKLNSPEETAFQTPKSSQMPRPSVPPLVKTSLFSSKLSTPDVVSPFGTPFGSSVMNRMAGIFDVNTCYGSPQSPQLIRR
SQ  GPRLWTSASDQQMTEFSNPSPSTSISAEGKTMRQPSVIYSWIQNKREQIKNFLSKRVLIMYFFSKHPEASIQAVFSDAQM
SQ  HIWALEGLSHLVAASFTEDRFGVVQTTLPAILNTLLTLQEAVDKYFKLPHASSKPPRISGSLVDTSYKTLRFAFRASLKT
SQ  AIYRITTTFGEHLNAVQASAEHQKRLQQFLEFKE
//