ID  Q9BXU9;
PN  Calcium-binding protein 8;
GN  CALN1;
OS  9606;
SL  Nucleus Position: SL-0198;
SL  Comments: Golgi apparatus, trans-Golgi network membrane {ECO:0000305|PubMed:19338761}; Single-pass type IV membrane protein {ECO:0000305|PubMed:19338761}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:19338761}. Cell membrane {ECO:0000305|PubMed:19338761}; Single-pass type IV membrane protein {ECO:0000305|PubMed:19338761}.
DR  UNIPROT: Q9BXU9;
DR  UNIPROT: J3KQA7;
DR  Pfam: PF13499;
DR  PROSITE: PS00018;
DR  PROSITE: PS50222;
DR  OMIM: 607176;
DR  DisGeNET: 83698;
DE  Function: Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. May play a role in the physiology of neurons and is potentially important in memory and learning. {ECO:0000250|UniProtKB:Q06BI3}.
DE  Reference Proteome: Yes;
DE  Interaction: P62166; IntAct: EBI-21458640; Score: 0.27
DE  Interaction: Q96LL9; IntAct: EBI-24625155; Score: 0.56
DE  Interaction: Q9NZ43; IntAct: EBI-24630791; Score: 0.56
DE  Interaction: Q969F0; IntAct: EBI-24388353; Score: 0.56
DE  Interaction: Q96IW7; IntAct: EBI-24542608; Score: 0.56
DE  Interaction: P60201; IntAct: EBI-24602587; Score: 0.56
DE  Interaction: P21145; IntAct: EBI-24638394; Score: 0.56
DE  Interaction: P03973; IntAct: EBI-24807681; Score: 0.56
DE  Interaction: Q9H400; IntAct: EBI-25271079; Score: 0.56
DE  Interaction: Q58WW2; IntAct: EBI-21889878; Score: 0.40
DE  Interaction: P21554; IntAct: EBI-21458285; Score: 0.38
GO  GO:0016021;
GO  GO:0048471;
GO  GO:0005886;
GO  GO:0032588;
GO  GO:0005509;
TP  Membrane Topology: Transmembrane; Source: UniProt - Sequence Analysis {ECO:0000255};
SQ  MRLPEQPGEGKPENEKKGDGGALGGGEEPPRSQAPDFPTWEKMPFHHVTAGLLYKGNYLNRSLSAGSDSEQLANISVEEL
SQ  DEIREAFRVLDRDGNGFISKQELGMAMRSLGYMPSEVELAIIMQRLDMDGDGQVDFDEFMTILGPKLVSSEGRDGFLGNT
SQ  IDSIFWQFDMQRITLEELKHILYHAFRDHLTMKDIENIIINEEESLNETSGNCQTEFEGVHSQKQNRQTCVRKSLICAFA
SQ  MAFIISVMLIAANQILRSGME
//