ID  Q9D7I0;
PN  Protein shisa-5;
GN  Shisa5;
OS  10090;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0182;
SL  Comments: Endoplasmic reticulum membrane {ECO:0000269|PubMed:12135983}; Single-pass type I membrane protein {ECO:0000269|PubMed:12135983}. Nucleus membrane {ECO:0000269|PubMed:12135983}.
DR  UNIPROT: Q9D7I0;
DR  UNIPROT: Q8BJ86;
DR  UNIPROT: Q8BJ87;
DR  UNIPROT: Q8BLE9;
DR  UNIPROT: Q8K4W3;
DR  UNIPROT: Q91Z37;
DR  UNIPROT: Q9CQP5;
DR  Pfam: PF13908;
DE  Function: Can induce apoptosis in a caspase-dependent manner and plays a role in p53/TP53-dependent apoptosis. {ECO:0000269|PubMed:12135983}.
DE  Reference Proteome: Yes;
DE  Interaction: P12815; IntAct: EBI-6857545; Score: 0.35
GO  GO:0005783;
GO  GO:0005789;
GO  GO:0016021;
GO  GO:0005635;
GO  GO:0031965;
GO  GO:0050699;
GO  GO:0072332;
GO  GO:0042771;
TP  Membrane Topology: Transmembrane; Source: UniProt - Sequence Analysis {ECO:0000255};
SQ  MAAPAPSLWTLLLLLLLLPPPPGAHGELCRPFGEDNSIPVFCPDFCCGSCSNQYCCSDVLRKIQWNEEMCPEPESRFSTP
SQ  AEETPEHLGSALKFRSSFDSDPMSGFGATVAIGVTIFVVFIATIIICFTCSCCCLYKMCCPQRPVVTNTTTTTVVHAPYP
SQ  QPQPQPVAPSYPGPTYQGYHPMPPQPGMPAAPYPTQYPPPYLAQPTGPPPYHESLAGASQPPYNPTYMDSLKTIP
//