ID  Q9DA32;
PN  SUN domain-containing protein 5;
GN  Sun5;
OS  10090;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0179;
SL  Nucleus Position: SL-0182;
SL  Comments: Nucleus inner membrane {ECO:0000269|PubMed:21159740, ECO:0000269|PubMed:25775128, ECO:0000269|PubMed:28945193, ECO:0000269|PubMed:29298896}; Single-pass membrane protein {ECO:0000269|PubMed:21159740}. Golgi apparatus {ECO:0000269|PubMed:25775128}. Note=During spermiogenesis, traffics through the Golgi apparatus before reaching the round spermatid inner membrane of the nuclear envelope and later migrates to the coupling apparatus of the sperm during sperm head elongation and differentiation. In mature spermatozoa, is localized to the coupling apparatus of the sperm head and tail in the implementation fossa. {ECO:0000269|PubMed:21159740, ECO:0000269|PubMed:25775128, ECO:0000269|PubMed:28945193}.
DR  UNIPROT: Q9DA32;
DR  UNIPROT: D2DR64;
DR  UNIPROT: Q5DT38;
DR  Pfam: PF07738;
DR  PROSITE: PS51469;
DE  Function: Plays an essential role in anchoring sperm head to the tail. Is responsible for the attachment of the coupling apparatus to the sperm nuclear envelope. {ECO:0000269|PubMed:28945193, ECO:0000305|PubMed:21711156}.
DE  Reference Proteome: Yes;
GO  GO:0005794;
GO  GO:0005639;
GO  GO:0034993;
GO  GO:0005635;
GO  GO:0005637;
GO  GO:0097224;
GO  GO:0043495;
GO  GO:0006998;
GO  GO:0007286;
GO  GO:0007283;
TP  Membrane Topology: Transmembrane; Source: UniProt - Sequence Analysis {ECO:0000255};
SQ  MPRTRNIGALCTLPEDTTHSGRPRRGVQRSYISRMAEPAPANMNDPLLLPLRMNTPGLSLVQILLGYMSWLTYLACFLRT
SQ  QTQQVFLNTCRCKLFCQKVMEKMGLLVLCVFGFWMFSMHLPSKVEVWQDDSINGPLQSLRMYQEKVRHHTGEIQDLRGSM
SQ  NQLIAKLQKMEAISDEQKMAQKIMKMIQGDYIEKPDFALKSIGASIDFEHTSATYNHDKARSYWNWIRLWNYAQPPDVIL
SQ  EPNVTPGNCWAFASDRGQVTIRLAQKVYLSNITLQHIPKTISLSGSPDTAPKDIVIYGLESLPREEVFLGAFQFQPENVI
SQ  QMFQLQNLPPRSFAAVKVKISSNWGNPRFTCMYRVRVHGSVTPPKDSHLEPLS
//