ID  Q9DA97;
PN  Septin-14;
GN  Septin14;
OS  10090;
SL  Nucleus Position: SL-0198;
SL  Comments: Cytoplasm {ECO:0000269|PubMed:20181826}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:33228246}. Cell projection, axon {ECO:0000269|PubMed:20181826}. Cell projection, dendrite {ECO:0000269|PubMed:20181826}. Perikaryon {ECO:0000269|PubMed:20181826}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:33228246}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250|UniProtKB:Q6ZU15}. Note=Colocalizes with actin stress fibers (By similarity). Expressed in the perinuclear rim and manchette structure in early elongating spermatids during spermiogenesis (PubMed:33228246). {ECO:0000250|UniProtKB:Q6ZU15, ECO:0000269|PubMed:33228246}.
DR  UNIPROT: Q9DA97;
DR  UNIPROT: E9QMM2;
DR  Pfam: PF00735;
DR  PROSITE: PS51719;
DE  Function: Filament-forming cytoskeletal GTPase (Probable). Involved in the migration of cortical neurons and the formation of neuron leading processes during embryonic development (PubMed:20181826). Plays a role in sperm head formation during spermiogenesis, potentially via facilitating localization of ACTN4 to cell filaments (By similarity). {ECO:0000250|UniProtKB:Q6ZU15, ECO:0000269|PubMed:20181826, ECO:0000305}.
DE  Reference Proteome: Yes;
GO  GO:0001669;
GO  GO:0030424;
GO  GO:0032153;
GO  GO:0005737;
GO  GO:0005856;
GO  GO:0030425;
GO  GO:0015630;
GO  GO:0043204;
GO  GO:0048471;
GO  GO:0031105;
GO  GO:0005940;
GO  GO:0005525;
GO  GO:0003924;
GO  GO:0060090;
GO  GO:0061640;
GO  GO:0001764;
GO  GO:0008104;
GO  GO:1905719;
GO  GO:0007286;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MAEKPTNTSVPIPGSEDPQKENIRCLSTLGHFGFECLPTQLVNKSIQKGFSFNILCVGETGIGKTTLINTLFNTNLKETK
SQ  SSHFYSKVGLTVKTYELLERNIPLRLTVVKTVGYGDQINKEASYQPVVDYLDAQFEAYLQEELKIKRSLADYHDSRIHVC
SQ  LYFITPTGHSLKSLDLLTMKSIDRRVNIIPLIAKADSLSKNDLQRFKNNIMSELNSNGIQIYQFQVDDEASAQVNSSGLL
SQ  PFAVVGSMEEVKVGKRMVRGRHYPWGVLQEVENENHCDFVKLRDLLLSTNMEDLKDQTHTQHYECYRSNRLQKLGFSDTG
SQ  PDNRPVSFQEMYEAKRREFHNQCQKEEEELKQTFMQRVKEKELTFKDAEKELQDKFEHLKRIQQEEILKLEEERRKLEEQ
SQ  IIDFYKMKAASESAQAQVCTNIKKDKDRKK
//