ID  Q9ER24;
PN  Ataxin-10;
GN  Atxn10;
OS  10116;
SL  Nucleus Position: SL-0198;
SL  Comments: Cytoplasm {ECO:0000269|PubMed:15201271}. Cytoplasm, perinuclear region {ECO:0000250}.
DR  UNIPROT: Q9ER24;
DR  Pfam: PF09759;
DE  Function: Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis. {ECO:0000269|PubMed:15201271, ECO:0000269|PubMed:16498633, ECO:0000269|PubMed:16714295}.
DE  Reference Proteome: Yes;
DE  Interaction: Q969Q1; IntAct: EBI-21997483; Score: 0.35
DE  Interaction: P35968; IntAct: EBI-22252817; Score: 0.35
DE  Interaction: Q92835; IntAct: EBI-22260778; Score: 0.35
DE  Interaction: P42681; IntAct: EBI-22265546; Score: 0.35
GO  GO:0005737;
GO  GO:0005829;
GO  GO:0030425;
GO  GO:0043025;
GO  GO:0048471;
GO  GO:0019899;
GO  GO:0042802;
GO  GO:0060271;
GO  GO:0007399;
GO  GO:0031175;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MAAPRMPPSRLSGIMVPAPIQDLEALRALTALFKEQRNRETAPRTIFQRVLDILKKSTQAVELACRDPSQVEHLASSLQL
SQ  ITECFRCLRNACIECSVNQNSIRNLDTIGVAVDLVLLFRELRVEQDSLLTAFRCGLQFLGNVASRNEDSQSIVWVHAFPE
SQ  LFMSCLNHPDKKIVAYCSMILFTSLNSERMKDLEENLNIAINVIEAHQKHPESEWPFLIITDHFLKSPELVEAMYGKLSN
SQ  QERVTLLDIMIAKIVGDEQLTKDDISIFLRHAELIANSFVDQCRNVLKLTSEPQTEDKEALVTIRLLDVLCEMTSNTELL
SQ  GYLQVFPGLMERVIDVLRVIHSVGKDSTNIFSPSDSLKAEGDIEHMTEGFKSHLIRLIGNLCYKNKENQDKVNELDGIPL
SQ  ILDSSNIDDNNPFMMQWVVYAVRNLTEDNSQNQDFIAKMEEQGLADASLLKKMGFEVEKSGDKLILKSNNDIPPP
//