ID  Q9FYP9;
PN  Importin subunit alpha-2;
GN  P0011G08;
OS  39947;
SL  Nucleus Position: SL-0198;
SL  Comments: Cytoplasm, perinuclear region.
DR  UNIPROT: Q9FYP9;
DR  UNIPROT: O80332;
DR  UNIPROT: Q0JQJ0;
DR  Pfam: PF00514;
DE  Function: Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Promotes docking of import substrates to the nuclear envelope. {ECO:0000269|PubMed:11124253}.
DE  Reference Proteome: Yes;
GO  GO:0005634;
GO  GO:0048471;
GO  GO:0061608;
GO  GO:0008139;
GO  GO:0006607;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MADDSASPSPSSASPLQHHREALKSSVRNTAASRRREQAIAIGKERREALIRAKRVCRAPISGSDEAEMEEGDMVVDEEK
SQ  ACLEAKTAHAVEELKSALSIQGKGVQKKKIEALRDLRRLLSQPEVPLVDTAIKAGAVPLLVQYLSFGSSDEQLLEAAWCL
SQ  TNIAAGEPEETKSLLPALPLLIAHLGEKSSTLVAEQCAWAIGNVAGEGAELRSTLLAQGALRPLTRLMFSSKGSTARTAA
SQ  WAMSNLIKGPDPKAANELITIDGVLNAIIASLEKEDEELATEVAWVVVYLSALSDRGISLIVRSSVPQLLIGRLFSSENL
SQ  QLLIPVLRGLGNLIAADDYMVDSVLTVGHNIIDQALSGLIKCLKSDNRVLRKESSWALSNIAAGSFEHKKLIFASEATPV
SQ  LIRLVTSMQFDIRREAAYTLGNLCVVPTGNCELPKIIVEHLVAIVDGGALPGFIHLVRSADVDTAGLGLQFLELVMRGYP
SQ  NKQGPKLVEMEDGIEAMERFQFHENEQMRNMANGLVDEYFGEDYGLDE
//