ID  Q9H7C4;
PN  Syncoilin;
GN  SYNC;
OS  9606;
SL  Nucleus Position: SL-0198;
SL  Comments: Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q9EPM5}. Note=In skeletal muscle, colocalizes with DES and DTNA, and is localized at the myotendinous and neuromuscular junctions, sarcolemma and Z-lines. In myotubes, detected in a punctate cytoplasmic pattern (By similarity). {ECO:0000250|UniProtKB:Q9EPM5}.
DR  UNIPROT: Q9H7C4;
DR  UNIPROT: B4DNK8;
DR  UNIPROT: B4DY58;
DR  UNIPROT: C9IY41;
DR  Pfam: PF00038;
DR  PROSITE: PS51842;
DR  OMIM: 611750;
DR  DisGeNET: 81493;
DE  Function: Atypical type III intermediate filament (IF) protein that may play a supportive role in the efficient coupling of mechanical stress between the myofibril and fiber exterior. May facilitate lateral force transmission during skeletal muscle contraction. Does not form homofilaments nor heterofilaments with other IF proteins. {ECO:0000250|UniProtKB:Q9EPM5}.
DE  Reference Proteome: Yes;
DE  Interaction: Q13137; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: Q13393; IntAct: EBI-25882515; Score: 0.56
DE  Interaction: Q9BV73; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: P08670; IntAct: EBI-25896426; Score: 0.56
DE  Interaction: Q8TEQ6; IntAct: EBI-11086338; Score: 0.35
DE  Interaction: P20152; IntAct: EBI-11150248; Score: 0.35
DE  Interaction: O15061; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: Q9Y6K9; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: Q9Y2X7; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: Q9P2K6; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: Q9NS87; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: Q9H2U2; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: Q9H2C0; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: Q9BZF9; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: Q96T51; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: Q96JN2; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: Q96EK4; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: Q96A19; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: Q8TBA6; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: Q8IWJ2; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: Q6P4E1; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: Q5JTD0; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: Q53EZ4; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: Q16352; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: Q15750; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: Q15276; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: Q15052; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: Q15025; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: Q14BN4; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: Q14161; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: Q14155; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: Q08378; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: P48681; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: P41219; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: P25054; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: P23508; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: P17661; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: P14136; IntAct: EBI-25858572; Score: 0.56
DE  Interaction: P07197; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: P07196; IntAct: EBI-25877887; Score: 0.56
DE  Interaction: O43318; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: O14777; IntAct: EBI-21702482; Score: 0.35
DE  Interaction: P61604; IntAct: EBI-20900543; Score: 0.40
DE  Interaction: Q8TDR0; IntAct: EBI-21389780; Score: 0.00
DE  Interaction: P68133; IntAct: EBI-25830425; Score: 0.56
DE  Interaction: P13637; IntAct: EBI-25832791; Score: 0.56
DE  Interaction: P16284; IntAct: EBI-25881579; Score: 0.56
DE  Interaction: P20339; IntAct: EBI-25889147; Score: 0.56
DE  Interaction: O76024; IntAct: EBI-25899416; Score: 0.56
DE  Interaction: O60333; IntAct: EBI-25916238; Score: 0.56
GO  GO:0005829;
GO  GO:0005882;
GO  GO:0031594;
GO  GO:0048471;
GO  GO:0042383;
GO  GO:0030018;
GO  GO:0045103;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MASPEPRRGGDGAAQAARKTRVEANSPLPKNSGSLNEAEALNPEVTLSSEGSLNLEDILYLEDTGDLDETLYVQETEKAE
SQ  EALYIEEAMQPDEALHVEEPGNPEETVCVEETTEPDRIQFVEGPVEPGKPTSPEHVVYEGETVTRAEKSNPEESLRAEQS
SQ  PSMEENLSIEDLELLEGRFQQCVQAVAQLEEERDQLIHELVLLREPALQEVQQVHQDILAAYKLHAQAELERDGLREEIR
SQ  LVKQKLFKVTKECVAYQYQLECRQQDVAQFADFREVLTTRATQLSEELAQLRDAYQKQKEQLRQQLEAPPSQRDGHFLQE
SQ  SRRLSAQFENLMAESRQDLEEEYEPQFLRLLERKEAGTKALQRTQAEIQEMKEALRPLQAEARQLRLQNRNLEDQIALVR
SQ  QKRDEEVQQYREQLEEMEERQRQLRNGVQLQQQKNKEMEQLRLSLAEELSTYKAMLLPKSLEQADAPTSQAGGMETQSQG
SQ  AV
//