ID  Q9N4A7;
PN  Protein SEC13 homolog;
GN  npp;
OS  6239;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0185;
SL  Comments: Cytoplasmic vesicle, COPII-coated vesicle membrane {ECO:0000250|UniProtKB:P55735}; Peripheral membrane protein {ECO:0000250|UniProtKB:P55735}; Cytoplasmic side {ECO:0000250|UniProtKB:P55735}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:21478858}; Peripheral membrane protein {ECO:0000250|UniProtKB:P55735}; Cytoplasmic side {ECO:0000250|UniProtKB:P55735}. Nucleus, nuclear pore complex {ECO:0000269|PubMed:21478858}. Lysosome membrane {ECO:0000250|UniProtKB:P55735}. Note=Localizes close to endoplasmic reticulum exit sites (ERES) and the nuclear envelopes of proliferating germ nuclei. {ECO:0000269|PubMed:21478858}.
DR  UNIPROT: Q9N4A7;
DR  UNIPROT: Q9N4A6;
DR  Pfam: PF00400;
DR  PROSITE: PS50082;
DR  PROSITE: PS50294;
DE  Function: Functions as a component of the nuclear pore complex (NPC) and the COPII coat (By similarity). Required for the nuclear import of hcp-4 during mitotic prophase, this step is essential for centrosome assembly and resolution (PubMed:28122936). {ECO:0000250|UniProtKB:P55735, ECO:0000269|PubMed:28122936}. As a component of the GATOR complex may function in the amino acid-sensing branch of the TORC1 signaling pathway. {ECO:0000250|UniProtKB:P55735}.
DE  Reference Proteome: Yes;
DE  Interaction: O01870; IntAct: EBI-335258; Score: 0.00
DE  Interaction: H2KZQ8; IntAct: EBI-2416122; Score: 0.49
DE  Interaction: P34643; IntAct: EBI-2421514; Score: 0.49
DE  Interaction: Q9XWR1; IntAct: EBI-6456137; Score: 0.37
DE  Interaction: Q1ZXS5; IntAct: EBI-6457496; Score: 0.37
DE  Interaction: P91001; IntAct: EBI-6460971; Score: 0.37
DE  Interaction: Q03563; IntAct: EBI-6462989; Score: 0.37
GO  GO:0030127;
GO  GO:0005789;
GO  GO:0005765;
GO  GO:0005643;
GO  GO:0031080;
GO  GO:0005198;
GO  GO:0051301;
GO  GO:0090114;
GO  GO:0009792;
GO  GO:1990893;
GO  GO:0051028;
GO  GO:0051169;
GO  GO:0006997;
GO  GO:0010973;
GO  GO:0032008;
GO  GO:1904263;
GO  GO:0032527;
GO  GO:0006606;
TP  Membrane Topology: Peripheral; Source: UniProt - By Similarity {ECO:0000250|UniProtKB:P55735};
SQ  MTTVRQRIDTQHRDAIHDAQLNIYGSRLATCGSDRLVKIFEVRPNGQSYPMAELVGHSGPVWKVSWAHPKYGGLLASASY
SQ  DKKVIIWNEQQGRWQKAYEWAAHEASTTCVAFAPHQYGLMLASASADGDIGILRYDNSSNEWISSKIQKCHEQGVNSVCW
SQ  APGSADPAAKKRLVSAGNDKNVKIWAFDDATNEWILEKTLAGHTDFVREAAWCPVTNNGQHTIVSCGMEGNLVLFRTSNI
SQ  ETEEWKAKLLETAPCALYHSSFSPCGSFLSVAGDDNVITIWRENLQGQWIKVPRDNKEREGMSQAVGAPGAQR
//