ID  Q9SMV6;
PN  Protein EXPORTIN 1A;
GN  XPO1;
OS  3702;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0182;
SL  Nucleus Position: SL-0185;
SL  Comments: Nucleus, nuclear pore complex {ECO:0000250|UniProtKB:Q9TVM2}. Nucleus membrane {ECO:0000250|UniProtKB:Q9TVM2}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9TVM2}; Nucleoplasmic side {ECO:0000250|UniProtKB:Q9TVM2}.
DR  UNIPROT: Q9SMV6;
DR  UNIPROT: F4KFL2;
DR  Pfam: PF08767;
DR  Pfam: PF18777;
DR  Pfam: PF18784;
DR  Pfam: PF18787;
DR  Pfam: PF03810;
DR  Pfam: PF08389;
DR  PROSITE: PS50166;
DE  Function: Receptor for the leucine-rich nuclear export signal (NES). Binds cooperatively to the NES on its target protein and to the small GTPase Ran in its active GTP-bound form (PubMed:10652141, PubMed:16766674). Required for the maternal-to-embryonic transition and during gametophyte development (PubMed:18791220). Involved in heat- induced oxidative stress basal resistance (PubMed:20345641). {ECO:0000269|PubMed:10652141, ECO:0000269|PubMed:16766674, ECO:0000269|PubMed:18791220, ECO:0000269|PubMed:20345641}.
DE  Reference Proteome: Yes;
DE  Interaction: Q67Y93; IntAct: EBI-1647715; Score: 0.37
DE  Interaction: Q941D1; IntAct: EBI-1647730; Score: 0.37
GO  GO:0005737;
GO  GO:0031965;
GO  GO:0005643;
GO  GO:0005634;
GO  GO:0005049;
GO  GO:0031267;
GO  GO:0009553;
GO  GO:0051028;
GO  GO:0009555;
GO  GO:0009846;
GO  GO:0009860;
GO  GO:0006611;
GO  GO:0009408;
GO  GO:0000055;
GO  GO:0000056;
TP  Membrane Topology: Peripheral; Source: UniProt - By Similarity {ECO:0000250|UniProtKB:Q9TVM2};
SQ  MAAEKLRDLSQPIDVGVLDATVAAFFVTGSKEERAAADQILRDLQANPDMWLQVVHILQNTNSLDTKFFALQVLEGVIKY
SQ  RWNALPVEQRDGMKNYISEVIVQLSSNEASFRSERLYVNKLNVILVQIVKHDWPAKWTSFIPDLVAAAKTSETICENCMA
SQ  ILKLLSEEVFDFSRGEMTQQKIKELKQSLNSEFKLIHELCLYVLSASQRQDLIRATLSALHAYLSWIPLGYIFESTLLET
SQ  LLKFFPVPAYRNLTIQCLTEVAALNFGDFYNVQYVKMYTIFIGQLRIILPPSTKIPEAYSSGSGEEQAFIQNLALFFTSF
SQ  FKFHIRVLESTPEVVSLLLAGLEYLINISYVDDTEVFKVCLDYWNSLVLELFDAHHNSDNPAVSASLMGLQPFLPGMVDG
SQ  LGSQVMQRRQLYSHPMSKLRGLMINRMAKPEEVLIVEDENGNIVRETMKDNDVLVQYKIMRETLIYLSHLDHDDTEKQML
SQ  RKLNKQLSGEEWAWNNLNTLCWAIGSISGSMAEDQENRFLVMVIRDLLNLCEITKGKDNKAVIASNIMYVVGQYPRFLRA
SQ  HWKFLKTVVNKLFEFMHETHPGVQDMACDTFLKIVQKCKRKFVIVQVGENEPFVSELLTGLATTVQDLEPHQIHSFYESV
SQ  GNMIQAESDPQKRDEYLQRLMALPNQKWAEIIGQARHSVEFLKDQVVIRTVLNILQTNTSAATSLGTYFLSQISLIFLDM
SQ  LNVYRMYSELVSTNITEGGPYASKTSFVKLLRSVKRETLKLIETFLDKAEDQPHIGKQFVPPMMESVLGDYARNVPDARE
SQ  SEVLSLFATIINKYKATMLDDVPHIFEAVFQCTLEMITKNFEDYPEHRLKFFSLLRAIATFCFPALIKLSSPQLKLVMDS
SQ  IIWAFRHTERNIAETGLNLLLEMLKNFQQSEFCNQFYRSYFMQIEQEIFAVLTDTFHKPGFKLHVLVLQQLFCLPESGAL
SQ  TEPLWDATTVPYPYPDNVAFVREYTIKLLSSSFPNMTAAEVTQFVNGLYESRNDPSGFKNNIRDFLVQSKEFSAQDNKDL
SQ  YAEEAAAQRERERQRMLSIPGLIAPNEIQDEMVDS
//