ID  Q9U1H9;
PN  Nuclear RNA export factor 1;
GN  sbr;
OS  7227;
SL  Nucleus Position: SL-0178;
SL  Comments: Nucleus, nucleoplasm {ECO:0000269|PubMed:14729961}. Cytoplasm {ECO:0000269|PubMed:14729961}. Nucleus envelope {ECO:0000269|PubMed:14729961}. Note=Localized in the nucleoplasm and at both the nucleoplasmic and cytoplasmic faces of the nuclear pore complex. Shuttles between the nucleus and the cytoplasm. {ECO:0000269|PubMed:14729961}.
DR  UNIPROT: Q9U1H9;
DR  UNIPROT: Q9NFQ2;
DR  UNIPROT: Q9NFQ3;
DR  UNIPROT: Q9VZ65;
DR  UNIPROT: Q9VZ68;
DR  PDB: 6IHJ;
DR  Pfam: PF02136;
DR  Pfam: PF09162;
DR  Pfam: PF03943;
DR  PROSITE: PS51450;
DR  PROSITE: PS50177;
DR  PROSITE: PS51281;
DE  Function: Mediates the export of the majority of mRNAs from the nucleus to the cytoplasm (PubMed:11779805, PubMed:11780633, PubMed:11780634, PubMed:27016737). In ovarian follicle cells, plays a role in transposable element silencing regulation by enabling the nuclear export of flamenco (flam) transcripts and subsequent piRNA biogenesis (PubMed:33856346). {ECO:0000269|PubMed:11779805, ECO:0000269|PubMed:11780633, ECO:0000269|PubMed:11780634, ECO:0000269|PubMed:27016737, ECO:0000269|PubMed:33856346}.
DE  Reference Proteome: Yes;
DE  Interaction: Q9VFS4; IntAct: EBI-236273; Score: 0.00
DE  Interaction: Q9UKK6; IntAct: EBI-302158; Score: 0.35
DE  Interaction: Q9V3H8; IntAct: EBI-873824; Score: 0.27
DE  Interaction: Q9V813; IntAct: EBI-1631868; Score: 0.00
DE  Interaction: Q24114; IntAct: EBI-9931823; Score: 0.35
GO  GO:0005737;
GO  GO:0005635;
GO  GO:0031965;
GO  GO:0005654;
GO  GO:0005634;
GO  GO:0047485;
GO  GO:0043021;
GO  GO:0003723;
GO  GO:0006406;
GO  GO:0051168;
GO  GO:0016973;
GO  GO:0046833;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MPKRGGGSSQRYNNNVGNGGGRYNAPEDFDDFDVEDRQRRKDRNKRRVSFKPSQCLHNKKDIKLRPEDLRRWDEDDDMSD
SQ  MTTAVKDRPTSRRRGSPIPRGKFGKLMPNSFGWYQVTLQNAQIYEKETLLSALLAAMSPHVFIPQYWRVERNCVIFFTDD
SQ  YEAAERIQHLGKNGHLPDGYRLMPRVRSGIPLVAIDDAFKEKMKVTMAKRYNIQTKALDLSRFHADPDLKQVFCPLFRQN
SQ  VMGAAIDIMCDNIPDLEALNLNDNSISSMEAFKGVEKRLPNLKILYLGDNKIPSLAHLVVLRNLSILELVLKNNPCRSRY
SQ  KDSQQFISEVRRKFPKLVKLDGETLEPQITFDLSEQGRLLETKASYLCDVAGAEVVRQFLDQYFRIFDSGNRQALLDAYH
SQ  EKAMLSISMPSASQAGRLNSFWKFNRNLRRLLNGEENRTRNLKYGRLACVSTLDEWPKTQHDRRTFTVDLTIYNTSMMVF
SQ  TVTGLFKELNDETNNPASMELYDVRHFARTYVVVPQNNGFCIRNETIFITNATHEQVREFKRSQHQPAPGAMPSTSSAVT
SQ  SPQAGAAAGLQGRLNALGVATGPVAILSGDPLAATAPVNSGSAAISTTAVAPGAQDESTKMQMIEAMSAQSQMNVIWSRK
SQ  CLEETNWDFNHAAFVFEKLFKENKIPPEAFMK
//