ID  Q9UL33;
PN  Trafficking protein particle complex subunit 2-like protein;
GN  TRAPPC2L;
OS  9606;
SL  Nucleus Position: SL-0198;
SL  Comments: Cytoplasm, perinuclear region {ECO:0000269|PubMed:19416478}. Endoplasmic reticulum {ECO:0000269|PubMed:19416478}. Golgi apparatus {ECO:0000269|PubMed:19416478}.
DR  UNIPROT: Q9UL33;
DR  UNIPROT: B2R4M9;
DR  UNIPROT: Q6ZTA7;
DR  UNIPROT: Q9NZZ4;
DR  Pfam: PF04628;
DR  OMIM: 610970;
DR  OMIM: 618331;
DR  DisGeNET: 51693;
DE  Function: Plays a role in vesicular transport from endoplasmic reticulum to Golgi. {ECO:0000269|PubMed:19416478, ECO:0000269|PubMed:30120216}.
DE  Disease: Encephalopathy, progressive, early-onset, with episodic rhabdomyolysis (PEERB) [MIM:618331]: An autosomal recessive disease characterized by progressive encephalopathy exacerbated by febrile illness and associated with severe neurodevelopmental delay, episodes of rhabdomyolysis, developmental regression, epilepsy and tetraplegia. {ECO:0000269|PubMed:30120216}. Note=The disease may be caused by variants affecting the gene represented in this entry.
DE  Reference Proteome: Yes;
DE  Interaction: P16278; IntAct: EBI-21692555; Score: 0.35
DE  Interaction: O43617; IntAct: EBI-755932; Score: 0.84
DE  Interaction: Q15063; IntAct: EBI-7067116; Score: 0.37
DE  Interaction: Q8NFH8; IntAct: EBI-7067203; Score: 0.37
DE  Interaction: P28838; IntAct: EBI-7067185; Score: 0.37
DE  Interaction: Q8NHS9; IntAct: EBI-7067302; Score: 0.37
DE  Interaction: Q8K3V1; IntAct: EBI-7067418; Score: 0.40
DE  Interaction: Q96QF0; IntAct: EBI-6160492; Score: 0.64
DE  Interaction: Q9Y2L5; IntAct: EBI-6550448; Score: 0.40
DE  Interaction: A5PLN9; IntAct: EBI-6550413; Score: 0.40
DE  Interaction: Q96D71; IntAct: EBI-10284496; Score: 0.56
DE  Interaction: Q04864; IntAct: EBI-10323488; Score: 0.56
DE  Interaction: P15884; IntAct: EBI-10323478; Score: 0.56
DE  Interaction: Q15654; IntAct: EBI-10323498; Score: 0.56
DE  Interaction: Q8IYX8; IntAct: EBI-10323512; Score: 0.56
DE  Interaction: Q9H2G9; IntAct: EBI-10323524; Score: 0.56
DE  Interaction: B2RXC1; IntAct: EBI-11119206; Score: 0.35
DE  Interaction: A0A286YCX6; IntAct: EBI-11119288; Score: 0.35
DE  Interaction: Q9NW68; IntAct: EBI-24509590; Score: 0.56
DE  Interaction: Q9H3H3; IntAct: EBI-24398603; Score: 0.56
DE  Interaction: O75865; IntAct: EBI-24609194; Score: 0.56
DE  Interaction: B2RXF5; IntAct: EBI-24625568; Score: 0.56
DE  Interaction: Q8TAP4; IntAct: EBI-24677401; Score: 0.56
DE  Interaction: P62487; IntAct: EBI-24715130; Score: 0.56
DE  Interaction: Q16385; IntAct: EBI-24717724; Score: 0.56
DE  Interaction: P50458; IntAct: EBI-24396478; Score: 0.56
DE  Interaction: Q6FHY5; IntAct: EBI-24449258; Score: 0.56
DE  Interaction: P50221; IntAct: EBI-24453529; Score: 0.56
DE  Interaction: Q15276; IntAct: EBI-24458111; Score: 0.56
DE  Interaction: O95872; IntAct: EBI-24592542; Score: 0.56
DE  Interaction: P80188; IntAct: EBI-24596447; Score: 0.56
DE  Interaction: A8MW99; IntAct: EBI-25216104; Score: 0.56
DE  Interaction: P48553; IntAct: EBI-11908313; Score: 0.00
DE  Interaction: Q8IYB1; IntAct: EBI-11921722; Score: 0.00
DE  Interaction: Q9NR12; IntAct: EBI-11933610; Score: 0.00
DE  Interaction: Q9Y5R8; IntAct: EBI-21546787; Score: 0.35
DE  Interaction: Q9Y296; IntAct: EBI-11938327; Score: 0.00
DE  Interaction: Q96Q05; IntAct: EBI-11938309; Score: 0.00
DE  Interaction: Q8TBN0; IntAct: EBI-11938300; Score: 0.00
DE  Interaction: Q8N9M5; IntAct: EBI-11938291; Score: 0.00
DE  Interaction: Q8IUR0; IntAct: EBI-21546443; Score: 0.35
DE  Interaction: Q9P2M4; IntAct: EBI-21546672; Score: 0.35
DE  Interaction: Q9BZR8; IntAct: EBI-21693005; Score: 0.35
DE  Interaction: Q96KC9; IntAct: EBI-21692950; Score: 0.35
DE  Interaction: Q8WVT3; IntAct: EBI-21756916; Score: 0.35
DE  Interaction: O43493; IntAct: EBI-16800265; Score: 0.27
DE  Interaction: P09613; IntAct: EBI-21497303; Score: 0.35
GO  GO:0005737;
GO  GO:0005829;
GO  GO:0005783;
GO  GO:0043231;
GO  GO:0005634;
GO  GO:0048471;
GO  GO:0030008;
GO  GO:1990071;
GO  GO:1990072;
GO  GO:0048208;
GO  GO:0006888;
GO  GO:0006901;
GO  GO:0099022;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MAVCIAVIAKENYPLYIRSTPTENELKFHYMVHTSLDVVDEKISAMGKALVDQRELYLGLLYPTEDYKVYGYVTNSKVKF
SQ  VMVVDSSNTALRDNEIRSMFRKLHNSYTDVMCNPFYNPGDRIQSSRAFDNMVTSMMIQVC
//