ID  Q9USL4;
PN  Nucleoporin nup61;
GN  nup61;
OS  284812;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0185;
SL  Comments: Nucleus, nuclear pore complex {ECO:0000269|PubMed:10759889, ECO:0000269|PubMed:15116432, ECO:0000269|PubMed:16823372}.
DR  UNIPROT: Q9USL4;
DR  UNIPROT: Q9UTW5;
DR  Pfam: PF08911;
DR  Pfam: PF00638;
DR  PROSITE: PS50196;
DE  Function: Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope. May play a role in mitotic spindle formation and/or function. {ECO:0000269|PubMed:15116432}.
DE  Reference Proteome: Yes;
GO  GO:0005737;
GO  GO:0140599;
GO  GO:0034399;
GO  GO:0005643;
GO  GO:0005634;
GO  GO:0051028;
GO  GO:0006913;
GO  GO:0015031;
GO  GO:0050790;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MSKRGADHQLTKDQDDSDDDRHGPVEVPKEASADVMATRKIAKPKSRKRPTSGVSSPGIFANLAAKPVSLPASTTQFTFG
SQ  KPAVTANNDSDIHLKKRGLNKSFIDAVIKSVDNNPFGNLSPLFDEYRQHFSSIEKKPAEEQPTSNAVVSEVNPQQQKSQD
SQ  SSSFVTEKPASSEKEDKEKPLVPPGAPRFGFSAPALGSSFQFNSSAFTPKGSFGEKSATEAEAKEKETSSNQTATGTAAT
SQ  TTNQFSFNTAANPFAFAKKENEESKPLTPVFSFSTTMASADASKETKQTHETKDSKSEESKPSNNEKSENAVEPAKGNTM
SQ  SFSWTPDKPIKFDTPEKKFTFTNPLSSKKLPASSDVKPPSAAAVGFSFGTTTNPFSFAAPKSSFPTSSTPASVGAEKSEE
SQ  TSNGNKSEQEEKENGNDETRSNDSLVSGKGKGEENEDSVFETRAKIYRFDATSKSYSDIGIGPLKINVDRDTGSARILAR
SQ  VEGSGKLLLNVRLCQDFEYSLAGKKDVKVPAASTDGKSIEMYLIRVKEPSTAEKLLAELNEKKVSKSEN
//