ID  Q9V6B9;
PN  Probable nucleoporin Nup54;
GN  Nup54;
OS  7227;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0185;
SL  Comments: Nucleus, nuclear pore complex {ECO:0000269|PubMed:17682050}.
DR  UNIPROT: Q9V6B9;
DR  Pfam: PF13874;
DR  Pfam: PF18437;
DE  Function: Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope (PubMed:17682050). Essential for the nuclear import of nuclear localization signal (NLS)-containing proteins in an importin alpha/importin beta-dependent manner (PubMed:17682050). Together with Nup58, required for transposable element silencing regulation in ovarian follicle cells (PubMed:33856346). By interacting with the nuclear (Nxf1/Nxt1) and cytosolic (fs(1)Yb) components of the flamenco (flam) transcripts processing pathway, enables export and subsequent piRNA production (PubMed:33856346). {ECO:0000269|PubMed:17682050, ECO:0000269|PubMed:33856346}.
DE  Reference Proteome: Yes;
DE  Interaction: Q24568; IntAct: EBI-9944837; Score: 0.35
DE  Interaction: Q7JXF5; IntAct: EBI-280221; Score: 0.00
DE  Interaction: Q9VYL7; IntAct: EBI-210131; Score: 0.00
DE  Interaction: Q9W1H7; IntAct: EBI-211333; Score: 0.00
DE  Interaction: Q9VRQ6; IntAct: EBI-229016; Score: 0.00
DE  Interaction: Q9VTC2; IntAct: EBI-26758035; Score: 0.62
DE  Interaction: Q9VWG2; IntAct: EBI-235591; Score: 0.00
DE  Interaction: O46085; IntAct: EBI-239628; Score: 0.00
DE  Interaction: Q9VS32; IntAct: EBI-239804; Score: 0.00
DE  Interaction: Q8T965; IntAct: EBI-245172; Score: 0.00
DE  Interaction: Q8MRM0; IntAct: EBI-247382; Score: 0.00
DE  Interaction: A1Z6W6; IntAct: EBI-254610; Score: 0.00
DE  Interaction: Q24337; IntAct: EBI-255366; Score: 0.00
DE  Interaction: Q9V9V0; IntAct: EBI-258334; Score: 0.00
DE  Interaction: Q868Z9; IntAct: EBI-268388; Score: 0.00
DE  Interaction: Q9VLA6; IntAct: EBI-270817; Score: 0.00
DE  Interaction: Q9W1A4; IntAct: EBI-272165; Score: 0.00
DE  Interaction: Q9VGW6; IntAct: EBI-272342; Score: 0.00
DE  Interaction: Q9XZS4; IntAct: EBI-15179362; Score: 0.62
DE  Interaction: Q9VF05; IntAct: EBI-278296; Score: 0.00
DE  Interaction: Q9VTU4; IntAct: EBI-278648; Score: 0.00
DE  Interaction: Q9VM05; IntAct: EBI-280628; Score: 0.00
DE  Interaction: Q9VVT5; IntAct: EBI-281753; Score: 0.00
DE  Interaction: Q7KLE5; IntAct: EBI-284881; Score: 0.00
DE  Interaction: Q7JZJ3; IntAct: EBI-285067; Score: 0.00
DE  Interaction: Q8MQZ0; IntAct: EBI-501710; Score: 0.00
DE  Interaction: Q9VSJ8; IntAct: EBI-507431; Score: 0.37
DE  Interaction: P22469; IntAct: EBI-7377238; Score: 0.37
DE  Interaction: Q7KKI9; IntAct: EBI-2109600; Score: 0.37
DE  Interaction: Q6WAR0; IntAct: EBI-2109779; Score: 0.37
DE  Interaction: Q86B83; IntAct: EBI-2110644; Score: 0.37
DE  Interaction: P18824; IntAct: EBI-9923731; Score: 0.35
DE  Interaction: Q8I942; IntAct: EBI-15179462; Score: 0.49
DE  Interaction: Q8IR83; IntAct: EBI-15179442; Score: 0.49
DE  Interaction: Q95RR8; IntAct: EBI-15179422; Score: 0.49
DE  Interaction: Q9VZV3; IntAct: EBI-15179382; Score: 0.49
DE  Interaction: O97420; IntAct: EBI-26758013; Score: 0.49
DE  Interaction: Q9VPX6; IntAct: EBI-26758023; Score: 0.49
GO  GO:0005643;
GO  GO:0044613;
GO  GO:0017056;
GO  GO:0051028;
GO  GO:0006607;
GO  GO:0006999;
GO  GO:0006913;
GO  GO:0006606;
GO  GO:0036228;
GO  GO:0006605;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MSFFGSNTSLGATSTPAKTTGGLFGSPFGGTAATSQPAPAFGAQATSTPAFGAQPATSAFGAGSAFGATAAAPAFGAATG
SQ  TSAFGGSAFGSTPAFGAATTTTAGTGLGGGGFGGFGAAPATSQAGLFGAPATSAAPPAFSGFGQQAAASTAPASGFSGFG
SQ  TTTTSAPAFGGFGTSQSTGFGGGAFGSTFGKPANTTVTPGFGGFGGTSFMLGQPQQQPAPISADEAFAQSILNVSIFGDE
SQ  RDKIVAKWNYLQATWGTGKMFYSQSAAPVDITPENVMCRFKAIGYSRMPGKDNKLGLVALNFCRELSAVKPHQQQVIQTL
SQ  HSLFGSKPNMLVHIDSIKELENKKCQIVIYVEEKLQHAPNESKRILATELSNYLNQATLKPQLNNLGVVEALALVLPDED
SQ  QLREYLENPPRGVDPRMWRQANSDNPDPTLYIPVPMVGFNDLKWRVKCQEQETDTHALYIKKVESELTELKKRHATATAK
SQ  ILEHKRKLAELSHRILRIIVKQECTRKVGTSLTPEEEALRTKLQNMLAVVSAPTQFKGRLSELLSQMRMQRNQFAANGGA
SQ  EYALDKEAEDEMKTFLTMQQRAMEVLSDTVNKDLRALDVIIKGLPELRQS
//