ID  Q9VDV3;
PN  Nuclear pore complex protein Nup58;
GN  Nup58;
OS  7227;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0185;
SL  Comments: Nucleus, nuclear pore complex {ECO:0000269|PubMed:15086791}. Note=Present also in annulate lamellae pore complexes (ALPCs). {ECO:0000269|PubMed:15086791}.
DR  UNIPROT: Q9VDV3;
DR  UNIPROT: Q8SYM7;
DE  Function: Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane (PubMed:15086791). Together with Nup54, required for transposable element silencing regulation in ovarian follicle cells (PubMed:33856346). By interacting with the nuclear (Nxf1/Nxt1) and cytosolic (fs(1)Yb) components of the flamenco (flam) transcripts processing pathway, enables export and subsequent piRNA production (PubMed:33856346). {ECO:0000269|PubMed:15086791, ECO:0000269|PubMed:33856346}.
DE  Reference Proteome: Yes;
DE  Interaction: Q9VJ62; IntAct: EBI-201971; Score: 0.00
DE  Interaction: Q9VT59; IntAct: EBI-206923; Score: 0.00
DE  Interaction: Q9W1H5; IntAct: EBI-211350; Score: 0.00
DE  Interaction: Q9W0R9; IntAct: EBI-221208; Score: 0.00
DE  Interaction: Q9VL73; IntAct: EBI-227768; Score: 0.00
DE  Interaction: P19339; IntAct: EBI-268179; Score: 0.00
DE  Interaction: P40798; IntAct: EBI-270201; Score: 0.00
GO  GO:0005635;
GO  GO:0005643;
GO  GO:0008139;
GO  GO:0017056;
GO  GO:0051028;
GO  GO:0006913;
GO  GO:0015031;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MFTPTTNNAIGGATAATGAFAFGARPATTTAPPPSFGAATSTPTFGAAPATTSLFAAPAATPAFGAPAATPAFGAPASTP
SQ  GFGATSTAAPAFGTAAATPAFGIPAATSAFGAPAATPAFGAAAATPAFGAPAATPAFGAPAATSAFGAPAATTAFGAPAS
SQ  TQASAFGAPAPAVGTVAPTFSFATPATSAPTTAPPAFGFGTTATTAAAAMPASLSSGIGSFSFPKPQATTAASLNFNTTT
SQ  TTATAQPFNTGLKLGTTNATTTLGGGGIFSKPAGQAAAPAASTFVGLGGIDVTATQPKLGDNKQDGIKIKETQVPDEIIK
SQ  TVDGLKAYIKQQKTISSDIGRTSTSKFTNVSHEITNLKWALQNMATLVEGSNQQIRLMRQETVKAIQSLEMAQRTQDTPA
SQ  GLQFENNAPFQYFQCLVAKYEQDLIAFRQQIALTERHMHAISNPQSISPDDLKRGFRQLNESFISLAGRLHEVHQRVEEH
SQ  KEHYLNLRRYRLRDTTNVFERIDNPPLPTVEPQRISSGPTPFSNISALMNKSYAAAASSASNATGN
//