ID  Q9VVE2;
PN  Protein rogdi;
GN  rogdi;
OS  7227;
SL  Nucleus Position: SL-0178;
SL  Comments: Nucleus envelope {ECO:0000250|UniProtKB:Q9GZN7}. Presynapse {ECO:0000250|UniProtKB:Q4V7D2}. Cell projection, axon {ECO:0000250|UniProtKB:Q4V7D2}. Perikaryon {ECO:0000250|UniProtKB:Q4V7D2}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q4V7D2}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle {ECO:0000250|UniProtKB:Q4V7D2}. Note=Detected primarily at presynaptic sites on axons, and to a lesser degree in soma and dendrites. Not detected at post-synaptic sites. {ECO:0000250|UniProtKB:Q4V7D2}.
DR  UNIPROT: Q9VVE2;
DR  UNIPROT: Q32KF2;
DR  UNIPROT: Q8IQP4;
DR  UNIPROT: Q95T16;
DR  Pfam: PF10259;
DE  Function: Plays a role in promoting sleep by enhancing metabotropic transmission of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) in GABAergic neurons upstream of a wake-inducing dopaminergic pathway. {ECO:0000269|PubMed:28900300}.
DE  Reference Proteome: Yes;
DE  Interaction: Q9VCH1; IntAct: EBI-199512; Score: 0.00
DE  Interaction: Q9VY61; IntAct: EBI-216289; Score: 0.00
DE  Interaction: Q0E8K5; IntAct: EBI-220799; Score: 0.00
DE  Interaction: Q9VVC2; IntAct: EBI-226383; Score: 0.00
DE  Interaction: P11929; IntAct: EBI-234009; Score: 0.00
DE  Interaction: Q9VU23; IntAct: EBI-234639; Score: 0.00
DE  Interaction: Q9VYV9; IntAct: EBI-258534; Score: 0.00
DE  Interaction: P10734; IntAct: EBI-274719; Score: 0.00
DE  Interaction: Q7K4Z4; IntAct: EBI-278444; Score: 0.00
DE  Interaction: P62152; IntAct: EBI-283358; Score: 0.00
DE  Interaction: P42287; IntAct: EBI-509567; Score: 0.37
DE  Interaction: P18431; IntAct: EBI-9925534; Score: 0.60
DE  Interaction: Q9VJQ6; IntAct: EBI-26734859; Score: 0.49
GO  GO:0070161;
GO  GO:0030424;
GO  GO:0030425;
GO  GO:0005635;
GO  GO:0043204;
GO  GO:0043291;
GO  GO:0008021;
GO  GO:0048149;
GO  GO:0061534;
GO  GO:0030431;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MKMLADTEREEALNLQIEFEWVLRQEVHAILKQLRSILVECAHRFPVPLYENEGKKTEKFILTVSPDQLKAVLTLTGDAI
SQ  TQADISFKLCKAPSQTQRTSITHDSPWKLQQVQDAANHLQTAINHIDDVDDSYHFKTSDEVLHVIGNILDALQRGRNSLL
SQ  VPKKKPIDELIKGRNMKSLVPNLPEDLAVSFYLQSHKLIIAVYQLLNNQGTMRFDSRQAEASVQWLNDVLLLLMNGQKLC
SQ  QQLKDKISVFSVYKDFTVGSRSPSALSY
//