ID  Q9VXD6;
PN  Nuclear envelope integral membrane protein;
GN  Nemp;
OS  7227;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0179;
SL  Nucleus Position: SL-0182;
SL  Comments: Nucleus inner membrane {ECO:0000269|PubMed:32923640}; Multi-pass membrane protein {ECO:0000255}; Nucleoplasmic side {ECO:0000250|UniProtKB:B9X187}.
DR  UNIPROT: Q9VXD6;
DR  Pfam: PF10225;
DE  Function: Contributes to nuclear envelope stiffness in germ cells (PubMed:32923640). Required for male and female fertility (PubMed:32923640). {ECO:0000269|PubMed:32923640}.
DE  Reference Proteome: Yes;
DE  Interaction: Q24568; IntAct: EBI-9919289; Score: 0.35
DE  Interaction: O97365; IntAct: EBI-280446; Score: 0.00
DE  Interaction: Q29R10; IntAct: EBI-284034; Score: 0.00
DE  Interaction: P33450; IntAct: EBI-9991526; Score: 0.37
GO  GO:0005639;
GO  GO:0005635;
GO  GO:0071763;
TP  Membrane Topology: Transmembrane; Source: UniProt - Sequence Analysis {ECO:0000255};
SQ  MHSAGLLMLTVAGYFTSGIPGNTASSDVAYLTPGTYINLSENILGLQTLRTFCYPGKRLTVSSLFETVEFVLAIGSDDYS
SQ  QYGGKTPEEVLQHYKDKQSLFSITLFAQKRQLLQLSPFEQQCIGISSRQAYTVILNSIPLDLWRLAQFAVGILILFSARR
SQ  LAKNSVFYYLVGIVIGICASLLVVIYLAAKLFPRRTMMYGVLIGGWTIGFYVIKQLADNLRLILITYRDHVLGYLVITGL
SQ  ISFLICYRIGPPKNPRSQTIVMWVLQAIGAVMAYFSSWHTSAVIFIMVLVFVAHYFPISWTNQIKFMYRRRFPLKRRMLT
SQ  QEEYEQQTAVETSKSLADLRKYVNSPECKQWAVMGKLRDPLRFASFANGAPHLDDEEIEDHSRTIEESMDAAPEEESVEE
SQ  PEEDKPAELLPLPNSQFRYQQAARNSEPEPESESDDSEEEEFFEQEVDLRQVVQ
//