ID  Q9Z2F6;
PN  B-cell lymphoma 3 protein homolog;
GN  Bcl3;
OS  10090;
SL  Nucleus Position: SL-0198;
SL  Comments: Nucleus {ECO:0000269|PubMed:16713561}. Cytoplasm {ECO:0000269|PubMed:16713561}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:16713561}. Note=Ubiquitination via 'Lys-63'-linked ubiquitin chains is required for nuclear accumulation.
DR  UNIPROT: Q9Z2F6;
DR  Pfam: PF00023;
DR  Pfam: PF12796;
DR  PROSITE: PS50297;
DR  PROSITE: PS50088;
DE  Function: Contributes to the regulation of transcriptional activation of NF-kappa-B target genes. In the cytoplasm, inhibits the nuclear translocation of the NF-kappa-B p50 subunit (By similarity). In the nucleus, acts as transcriptional activator that promotes transcription of NF-kappa-B target genes. Contributes to the regulation of cell proliferation. {ECO:0000250, ECO:0000269|PubMed:16713561}.
DE  Reference Proteome: Yes;
DE  Interaction: Q80TQ2; IntAct: EBI-943890; Score: 0.67
GO  GO:0032996;
GO  GO:0033257;
GO  GO:0005737;
GO  GO:0005829;
GO  GO:0043231;
GO  GO:0030496;
GO  GO:0005654;
GO  GO:0005634;
GO  GO:0048471;
GO  GO:0005886;
GO  GO:0032991;
GO  GO:0140297;
GO  GO:0042826;
GO  GO:0030674;
GO  GO:0003713;
GO  GO:0003714;
GO  GO:0019730;
GO  GO:0006974;
GO  GO:0042742;
GO  GO:0042832;
GO  GO:0030330;
GO  GO:0030198;
GO  GO:0002268;
GO  GO:0002467;
GO  GO:0002455;
GO  GO:0007249;
GO  GO:0042771;
GO  GO:0002315;
GO  GO:0043066;
GO  GO:0045892;
GO  GO:0032717;
GO  GO:0032088;
GO  GO:0046426;
GO  GO:0070233;
GO  GO:0032720;
GO  GO:0045893;
GO  GO:0032729;
GO  GO:0032733;
GO  GO:0045944;
GO  GO:0045727;
GO  GO:0006606;
GO  GO:0042981;
GO  GO:0051101;
GO  GO:1901222;
GO  GO:0010225;
GO  GO:0009615;
GO  GO:0048536;
GO  GO:0070231;
GO  GO:0042088;
GO  GO:0045064;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MPRCPAGAMDEGPVDLRTRPKGTPGAALPLRKRPLRPASPEPATTRSPAGPLDALRSGCDVPVVPGPPHCVARPEALYYQ
SQ  GPLMPIYSTPTMAPHFPLLNLPTHPYSMICPMEHPLSADIAMATRVDEDGDTPLHIAVVQNNIAAVYRILSLFKLGSREV
SQ  DVHNNLRQTPLHLAVITTLPDMVRLLVTAGASPMALDRHGQTAIHLACEHRSPSCLQALLDSATSGSVDLEVRNYEGLTA
SQ  LHVAVNTGCQEAVLLLLERGADIDAVDIKSGRSPLIHAVENNSLNMVQLLLLHGANVNAQMYSGSSALHSASGRGLLPLV
SQ  RTLVRSGADSGLKNCHNDTPLMVARSRRVIDILRGKASRAASGSQPEPSPDQSATNSPESSSRLSSNGLQSSPSSSPSLS
SQ  PPKDAPGFPATPQNFFLPTTSTPAFLPFPGVLRGPGRPVPPSPAPGSS
//