A1YER2 Oxidoreductase HTATIP2 9595 None SL-0178 Cytoplasm {ECO:0000250}. Nucleus envelope {ECO:0000250}. UNIPROT A1YER2 Pfam PF13460 Oxidoreductase required for tumor suppression. NADPH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import (By similarity). {ECO:0000250}. GO:0005737 GO:0005829 GO:0005635 GO:0016491 GO:0004674 GO:0001525 GO:0006915 GO:0030154 GO:0051170 GO:0043068 GO:0045944 GO:0046777 GO:0045765 Unknown UniProt Sequence Analysis MAETEALSKLREDFRMQNKSVFILGASGETGRVLLKEILEQGLFSKVTLIGRRKLTFDEEAYKNVNQEVVDFEKLDDYASAFQGHDVGFCCLGTTRGKAGAEGFVRVDRDYVLKSAELAKAGGCKHFNLLSSKGADKSSKFLYLQVKGEVEAKVEELKFDRYSVFRPGVLLCDRQESRPGEWLVRKFFGSLPESWASGHSVPVVTVVRAMLNNVVRPRDKQMELLENKAIHDLGKAHGSLKP 242