A3GFS1 Nuclear NPL4 322104 None SL-0178 SL-0182 SL-0198 Cytoplasm, perinuclear region {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Nucleus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Localizes mainly at the nuclear periphery and the endoplasmic reticulum membrane. {ECO:0000250}. UNIPROT A3GFS1 Pfam PF05021 Pfam PF05020 PROSITE PS50249 Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity). {ECO:0000250}. GO:0005789 GO:0031965 GO:0048471 GO:0051028 GO:0015031 GO:0006511 Peripheral UniProt By Similarity {ECO:0000250} MSVTLRFRSREGTFRVAANPDADFLLVLEQLLSKISIEDVQNLYLSDKPNSKGELANGLCGKTVTELGLKNGDMLYASYEAATGSNPDSTTNITTSTNNHNSGSISIGHISIPTTTSGPRKVTQLPVDDVLEKDEGLIKRPLTKFCRHGAKGMCEFCSPLPPWDANYRKENAIKHMSYHAYLKELNELKNSKHNSSSYIAPLEEPNYSILLNCNEGHQPYPKGICSKCQPPPITLQLQKFRMVDHVEFATSSIMNNFIDVWRHTGVQRFGVMYGRYEPFDKVPLGIKAVVEAIYEPPQSGELDGITMLPWENEAEVDAIASELGIYKVGVVFTDLTDSGQKNGTVLCKRHKDSYFLSNLEILMAARNQIQHANITKFSSSGQFSSKFVTCVISGGLNGEIEPRSYQVSTSAEALVRADIITGSTQPSRLYVNSSNDRRYVPDVAYSELNEYGLEVKSNAKPTFPVDFLLVSLTDSFPVNPTPMFDTDSNFVIENRDFFNELQNLHAVSKYLNADTSGKGTSLCNFHFLVYLKRTNILGAQEFDLLLRFVRERQYEDYLHLVESPGWMTLITILEQST 577