<Entry>
<Accession>A5A6K6</Accession>
        <ProteinName>Protein</ProteinName>
        <GeneName>NDRG2</GeneName>
        <OS_id>9598</OS_id>
        <ReferenceProteome>None</ReferenceProteome>
        <SubcellularLocation>
<Location>SL-0198</Location>
<Comments>Cytoplasm {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Cell projection, growth cone {ECO:0000250}. Note=In neurons, seems to concentrate at axonal growth cone. Perinuclear in neurons (By similarity). {ECO:0000250}.</Comments>
</SubcellularLocation>
<CrossReferences>
<CrossReference>
<Database>UNIPROT</Database>
<ID>A5A6K6</ID>
</CrossReference>
<CrossReference>
<Database>Pfam</Database>
<ID>PF03096</ID>
</CrossReference>
</CrossReferences>
<Function>Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation (By similarity). {ECO:0000250}.</Function>
<OntologyTerms>
<Ontology>GO:0005737</Ontology>
<Ontology>GO:0030426</Ontology>
<Ontology>GO:0048471</Ontology>
<Ontology>GO:0030154</Ontology>
<Ontology>GO:0007399</Ontology>
<Ontology>GO:0007165</Ontology>
<Ontology>GO:0016055</Ontology>
</OntologyTerms>
<Topology>
        <Type>Unknown</Type>
        <Source>UniProt</Source>
        <Annotation>Sequence Analysis</Annotation>
        </Topology>
<Sequence>MAELQEVQITEEKPLLPGQTPEAAKTHSVETPYGSVTFTVYGTPKPKRPAILTYHDVGLNYKSCFQPLFQFEDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPSLDQLADMIPCVLQYLNFSTIIGVGVGAGAYILARYALNHPDTVEGLVLINIDPNAKRWMDWAAHKLTGLTSSIPEMILGHLFSQEELSGNSELIQKYRNIITHAPNLDNIELYWNSYNNRRDLNFERGGDITLKCPVMLVVGDQAPHEDAVVECNSKLDPTQTSFLKMADSGGQPQLTQPGKLTEAFKYFLQGMGYMASSCMTRLSRSRTASLTSAASVDGNRSRSRTLSQSSESGTLSSGPPGHTMEVSC</Sequence>
        <SequenceLength>357</SequenceLength>
        </Entry>