<Entry>
<Accession>G5EFV8</Accession>
        <ProteinName>Vacuolar</ProteinName>
        <GeneName>vps</GeneName>
        <OS_id>6239</OS_id>
        <ReferenceProteome>None</ReferenceProteome>
        <SubcellularLocation>
<Location>SL-0198</Location>
<Comments>Golgi apparatus, trans-Golgi network {ECO:0000269|PubMed:21613545}. Perikaryon {ECO:0000269|PubMed:27191843}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:27191843}. Note=Co-localizes with rab-2 to perinuclear puncta in the perikaryon. Co-localizes with the small GTPases rab-6.1 and rab-6.2 at Golgi structures (PubMed:21613545). {ECO:0000269|PubMed:21613545, ECO:0000269|PubMed:27191843}.</Comments>
</SubcellularLocation>
<CrossReferences>
<CrossReference>
<Database>UNIPROT</Database>
<ID>G5EFV8</ID>
</CrossReference>
<CrossReference>
<Database>UNIPROT</Database>
<ID>G5EFV9</ID>
</CrossReference>
<CrossReference>
<Database>Pfam</Database>
<ID>PF04129</ID>
</CrossReference>
</CrossReferences>
<Function>Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN) (PubMed:21613545). The GARP complex facilitates tethering as well as SNARE complex assembly at the Golgi (PubMed:21613545). Plays a role in the trafficking of cargo to dense-core vesicles, probably through association with the EARP-interacting protein eipr-1 (PubMed:27191843). Important for neuronal function (PubMed:27191843). {ECO:0000269|PubMed:21613545, ECO:0000269|PubMed:27191843}.</Function>
<Interactions>
<Interaction>
<Partner>O01839</Partner>
<IntAct>EBI-2411813</IntAct>
<Score>0.73</Score>
</Interaction>
<Interaction>
<Partner>Q09501</Partner>
<IntAct>EBI-335600</IntAct>
<Score>0.00</Score>
</Interaction>
<Interaction>
<Partner>P32743</Partner>
<IntAct>EBI-335609</IntAct>
<Score>0.00</Score>
</Interaction>
<Interaction>
<Partner>O61975</Partner>
<IntAct>EBI-335606</IntAct>
<Score>0.00</Score>
</Interaction>
<Interaction>
<Partner>Q20742</Partner>
<IntAct>EBI-335603</IntAct>
<Score>0.00</Score>
</Interaction>
<Interaction>
<Partner>Q22227</Partner>
<IntAct>EBI-335612</IntAct>
<Score>0.00</Score>
</Interaction>
<Interaction>
<Partner>Q22544</Partner>
<IntAct>EBI-335615</IntAct>
<Score>0.00</Score>
</Interaction>
<Interaction>
<Partner>P91820</Partner>
<IntAct>EBI-335621</IntAct>
<Score>0.00</Score>
</Interaction>
<Interaction>
<Partner>P34574</Partner>
<IntAct>EBI-335618</IntAct>
<Score>0.00</Score>
</Interaction>
<Interaction>
<Partner>Q9N575</Partner>
<IntAct>EBI-335624</IntAct>
<Score>0.00</Score>
</Interaction>
<Interaction>
<Partner>Q22639</Partner>
<IntAct>EBI-6398967</IntAct>
<Score>0.54</Score>
</Interaction>
<Interaction>
<Partner>P34561</Partner>
<IntAct>EBI-6395189</IntAct>
<Score>0.54</Score>
</Interaction>
<Interaction>
<Partner>Q22782</Partner>
<IntAct>EBI-6399389</IntAct>
<Score>0.46</Score>
</Interaction>
<Interaction>
<Partner>P34213</Partner>
<IntAct>EBI-6399381</IntAct>
<Score>0.46</Score>
</Interaction>
<Interaction>
<Partner>G5EFV8</Partner>
<IntAct>EBI-6398996</IntAct>
<Score>0.37</Score>
</Interaction>
<Interaction>
<Partner>Q20797</Partner>
<IntAct>EBI-6399555</IntAct>
<Score>0.37</Score>
</Interaction>
<Interaction>
<Partner>H2KZ72</Partner>
<IntAct>EBI-6399559</IntAct>
<Score>0.37</Score>
</Interaction>
<Interaction>
<Partner>P41941</Partner>
<IntAct>EBI-6399538</IntAct>
<Score>0.37</Score>
</Interaction>
<Interaction>
<Partner>Q21499</Partner>
<IntAct>EBI-6399564</IntAct>
<Score>0.37</Score>
</Interaction>
</Interactions>
<OntologyTerms>
<Ontology>GO:0005829</Ontology>
<Ontology>GO:0000938</Ontology>
<Ontology>GO:0005797</Ontology>
<Ontology>GO:0000138</Ontology>
<Ontology>GO:0043204</Ontology>
<Ontology>GO:0048471</Ontology>
<Ontology>GO:0031267</Ontology>
<Ontology>GO:0019905</Ontology>
<Ontology>GO:0032456</Ontology>
<Ontology>GO:0006896</Ontology>
<Ontology>GO:0007041</Ontology>
<Ontology>GO:1904810</Ontology>
<Ontology>GO:1904811</Ontology>
<Ontology>GO:0090326</Ontology>
<Ontology>GO:0015031</Ontology>
<Ontology>GO:0042147</Ontology>
</OntologyTerms>
<Topology>
        <Type>Unknown</Type>
        <Source>UniProt</Source>
        <Annotation>Sequence Analysis</Annotation>
        </Topology>
<Sequence>MPRTRVNLQKSEANDRSFTISSLEFCLSQLRKADPNLVKKAIASGDGLTESKNDVSTRLSEAHRYSVQQCLDNSEQLAQLHNQLVHCDNVFERLQATLYSFQDNLGSIGQDMKNLQLQSHHIHQELENRQKVRVELSQFVDDIAVSQTMMKTINDTDANDRGFLEALHELHHKITLILQRGNGDAVAVNDTMPILEGLKLKAVVKVREWLLQKMFQFRKPLSNYQVFQHQLLKCRFFYEFLLHHDLISAKELQDEYIDTISKMFFTYFKAYATRLFKLAMKDVATKEDALGSIDFAKPAGLGAIFSSKQHVVRNKATVFSIGQRHQILSDDFLGALIVPHAATQNHQSYQFEALFRSIQLAFVDHYSHEYLFITDFFLVSNDEAIELHNKAMARAMSVVLKSCEEQIALSWDAISLHLCICLCDKFTEVLAEREVPEVSDYWNTVTSFLWTRLNLVMSQHYESVKSVDLKKLMHSGSLDARPHFIVRRYAELTSAHLMIAKASGKEMGAKMEAVLENSEDSIEQLLTRMSAMQQTQKNKHVFLINNYDLILSIIDNEESKHTKIYAIVHELEQKSIDDFVEEMLEPHIGYMIKFVNECESLIVQGHTQLLVRYNDKVGTVVANFNAKWRPAVDSINSECIQLFTNFSLGTTILQTIFTKYVQYINRFTKILSHDVFAKNPVCSQLVNVHQVMLEIKRFKPAY</Sequence>
        <SequenceLength>702</SequenceLength>
        </Entry>