O94559 Nuclear les1 284812 None SL-0178 SL-0179 SL-0182 Nucleus inner membrane {ECO:0000269|PubMed:32848252}. Note=Concentrates at the stalk of each daughter nucleus during anaphase. {ECO:0000269|PubMed:32848252}. UNIPROT O94559 Pfam PF10281 Inner nuclear envelope protein involved in nuclear fission, which is achieved via local disassembly of nuclear pores within the narrow bridge that links segregating daughter nuclei (PubMed:32848252). Les1 restricts the process of local nuclear envelope breakdown to the bridge midzone to prevent the leakage of material from daughter nuclei during mitosis (PubMed:32848252). {ECO:0000269|PubMed:32848252}. GO:0140511 GO:0005637 GO:0051301 GO:0140515 GO:1905557 Unknown UniProt Sequence Analysis MQPRFLLHGALLALGIQLCLSIGKITGHISSIEATAADIHDAPSTTTKYVQRTVYAGREKGKIGGPADSWPQRKLDDFLQNHGVKSLDVPPIETPSQFWRKPLQYVSKVTDKCKSFYEKEKNHASHNAQKLDVWIFNSWTNSELSRWLIKNKYEVPEPGTREQLLETVFQASMGDAISTNDELESWSNNLLLSMLDQKNITVPIGASHDDLIVLARRYYDIEERKSQDKVTNITDSQPAPYMKEIIHLWSDGRLIDFLRERNIPISVLSPRETLLKEAYANRFTPRVMIASNVLDGWSSEDLLDWIWKYNKRGSIFSHVAYNSRHELIHAAKLFYMDVASEWSSSDMASLNDSLYSHPSVSKQSTWTEEELKEELESFGELVPVPFSSTKAFERLLPHLYYYLRGPAFLNRIHYWQTFLGNSLKRAFVLSQ 431