P20449 ATP-dependent DBP5 559292 None SL-0178 SL-0182 SL-0185 Cytoplasm. Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Nuclear pore complex cytoplasmic fibrils. Accumulates in the nucleus rapidly and reversibly in response to ethanol stress. UNIPROT P20449 UNIPROT D6W2B2 PDB 2KBE PDB 2KBF PDB 3GFP PDB 3PEU PDB 3PEV PDB 3PEW PDB 3PEY PDB 3RRM PDB 3RRN PDB 5ELX Pfam PF00270 Pfam PF00271 PROSITE PS00039 PROSITE PS51192 PROSITE PS51194 PROSITE PS51195 ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus. May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex. Contributes to the blocking of bulk poly(A)+ mRNA export in ethanol-stressed cells. May also be involved in early transcription. {ECO:0000269|PubMed:10428971, ECO:0000269|PubMed:10523319, ECO:0000269|PubMed:10610322, ECO:0000269|PubMed:11350039, ECO:0000269|PubMed:12192043, ECO:0000269|PubMed:12686617, ECO:0000269|PubMed:15280434, ECO:0000269|PubMed:15574330, ECO:0000269|PubMed:15619606, ECO:0000269|PubMed:9564047, ECO:0000269|PubMed:9564048}. Q02159 EBI-860380 0.00 P40477 EBI-7266119 0.66 Q04839 EBI-7998113 0.66 P50111 EBI-2132816 0.51 P32491 EBI-2617619 0.35 P40484 EBI-2617649 0.35 Q12529 EBI-2887496 0.00 P40564 EBI-3656740 0.35 P33416 EBI-3744163 0.35 P11484 EBI-3778915 0.35 P39987 EBI-3787386 0.35 P04147 EBI-7082780 0.40 Q12315 EBI-15806702 0.76 GO:0005934 GO:0005737 GO:0010494 GO:0031965 GO:0044614 GO:0005634 GO:0005844 GO:0005524 GO:0016887 GO:0008186 GO:0003723 GO:0003724 GO:0006406 GO:0016973 GO:0015031 GO:0006415 GO:0006409 Peripheral UniProt Sequence Analysis MSDTKRDPADLLASLKIDNEKEDTSEVSTKETVKSQPEKTADSIKPAEKLVPKVEEKKTKQEDSNLISSEYEVKVKLADIQADPNSPLYSAKSFDELGLAPELLKGIYAMKFQKPSKIQERALPLLLHNPPRNMIAQSQSGTGKTAAFSLTMLTRVNPEDASPQAICLAPSRELARQTLEVVQEMGKFTKITSQLIVPDSFEKNKQINAQVIVGTPGTVLDLMRRKLMQLQKIKIFVLDEADNMLDQQGLGDQCIRVKRFLPKDTQLVLFSATFADAVRQYAKKIVPNANTLELQTNEVNVDAIKQLYMDCKNEADKFDVLTELYGLMTIGSSIIFVATKKTANVLYGKLKSEGHEVSILHGDLQTQERDRLIDDFREGRSKVLITTNVLARGIDIPTVSMVVNYDLPTLANGQADPATYIHRIGRTGRFGRKGVAISFVHDKNSFNILSAIQKYFGDIEMTRVPTDDWDEVEKIVKKVLKD 482