P32567 Phosphatidic PAH1 559292 None SL-0178 SL-0182 Cytoplasm. Nucleus membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. UNIPROT P32567 UNIPROT D6VZY7 Pfam PF04571 Pfam PF08235 Mg(2+)-dependent phosphatidate (PA) phosphatase which catalyzes the dephosphorylation of PA to yield diacylglycerol (PubMed:16467296, PubMed:16968695, PubMed:17910939, PubMed:17971454, PubMed:20876142, PubMed:21081492, PubMed:29765047). Required for de novo lipid synthesis and formation of lipid droplets (PubMed:21422231). Controls transcription of phospholipid biosynthetic genes and nuclear structure by regulating the amount of membrane present at the nuclear envelope (PubMed:15889145). Involved in plasmid maintenance, in respiration and in cell proliferation (PubMed:8437575). {ECO:0000269|PubMed:15889145, ECO:0000269|PubMed:16467296, ECO:0000269|PubMed:16968695, ECO:0000269|PubMed:17910939, ECO:0000269|PubMed:17971454, ECO:0000269|PubMed:20876142, ECO:0000269|PubMed:21081492, ECO:0000269|PubMed:21422231, ECO:0000269|PubMed:29765047, ECO:0000269|PubMed:8437575}. P30822 EBI-11611503 0.35 P35719 EBI-390744 0.37 P16140 EBI-809535 0.35 P07259 EBI-809535 0.35 P02557 EBI-809535 0.35 P09733 EBI-809535 0.35 P11484 EBI-809535 0.53 P10592 EBI-809535 0.53 P00549 EBI-809535 0.35 P40038 EBI-2612835 0.35 P40150 EBI-3721470 0.35 P10591 EBI-3752559 0.35 Q06677 EBI-3758717 0.35 GO:0005737 GO:0005829 GO:0005789 GO:0019898 GO:0005811 GO:0031965 GO:0005634 GO:0005773 GO:0008195 GO:0000976 GO:0009060 GO:0044255 GO:0009062 GO:0034389 GO:0008654 GO:0006276 GO:0019432 GO:0042144 Peripheral UniProt Sequence Analysis MQYVGRALGSVSKTWSSINPATLSGAIDVIVVEHPDGRLSCSPFHVRFGKFQILKPSQKKVQVFINEKLSNMPMKLSDSGEAYFVFEMGDQVTDVPDELLVSPVMSATSSPPQSPETSILEGGTEGEGEGENENKKKEKKVLEEPDFLDINDTGDSGSKNSETTGSLSPTESSTTTPPDSVEERKLVEQRTKNFQQKLNKKLTEIHIPSKLDNNGDLLLDTEGYKPNKNMMHDTDIQLKQLLKDEFGNDSDISSFIKEDKNGNIKIVNPYEHLTDLSPPGTPPTMATSGSVLGLDAMESGSTLNSLSSSPSGSDTEDETSFSKEQSSKSEKTSKKGTAGSGETEKRYIRTIRLTNDQLKCLNLTYGENDLKFSVDHGKAIVTSKLFVWRWDVPIVISDIDGTITKSDALGHVLAMIGKDWTHLGVAKLFSEISRNGYNILYLTARSAGQADSTRSYLRSIEQNGSKLPNGPVILSPDRTMAALRREVILKKPEVFKIACLNDIRSLYFEDSDNEVDTEEKSTPFFAGFGNRITDALSYRTVGIPSSRIFTINTEGEVHMELLELAGYRSSYIHINELVDHFFPPVSLDSVDLRTNTSMVPGSPPNRTLDNFDSEITSGRKTLFRGNQEEKFTDVNFWRDPLVDIDNLSDISNDDSDNIDEDTDVSQQSNISRNRANSVKTAKVTKAPQRNVSGSTNNNEVLAASSDVENASDLVSSHSSSGSTPNKSTMSKGDIGKQIYLELGSPLASPKLRYLDDMDDEDSNYNRTKSRRASSAAATSIDKEFKKLSVSKAGAPTRIVSKINVSNDVHSLGNSDTESRREQSVNETGRNQLPHNSMDDKDLDSRVSDEFDDDEFDEDEFED 862