<Entry>
<Accession>P34077</Accession>
        <ProteinName>Nucleoporin</ProteinName>
        <GeneName>NIC96</GeneName>
        <OS_id>559292</OS_id>
        <ReferenceProteome>None</ReferenceProteome>
        <SubcellularLocation>
<Location>SL-0178</Location>
<Location>SL-0182</Location>
<Location>SL-0185</Location>
<Comments>Nucleus, nuclear pore complex {ECO:0000269|PubMed:10684247}. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Note=Symmetric distribution.</Comments>
</SubcellularLocation>
<CrossReferences>
<CrossReference>
<Database>UNIPROT</Database>
<ID>P34077</ID>
</CrossReference>
<CrossReference>
<Database>UNIPROT</Database>
<ID>D6VTN2</ID>
</CrossReference>
<CrossReference>
<Database>PDB</Database>
<ID>2QX5</ID>
</CrossReference>
<CrossReference>
<Database>PDB</Database>
<ID>2RFO</ID>
</CrossReference>
<CrossReference>
<Database>PDB</Database>
<ID>6X07</ID>
</CrossReference>
<CrossReference>
<Database>PDB</Database>
<ID>7N85</ID>
</CrossReference>
<CrossReference>
<Database>PDB</Database>
<ID>7N9F</ID>
</CrossReference>
<CrossReference>
<Database>PDB</Database>
<ID>7WOO</ID>
</CrossReference>
<CrossReference>
<Database>PDB</Database>
<ID>7WOT</ID>
</CrossReference>
<CrossReference>
<Database>Pfam</Database>
<ID>PF04097</ID>
</CrossReference>
</CrossReferences>
<Function>Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. NIC96, which is localized to the core of the NPC and the distal ring of the nuclear basket, is required for de novo assembly of NPCs. It is involved in nuclear GSP1 import. {ECO:0000269|PubMed:10428845, ECO:0000269|PubMed:10617624, ECO:0000269|PubMed:10684247, ECO:0000269|PubMed:10806080, ECO:0000269|PubMed:11121302, ECO:0000269|PubMed:11689687, ECO:0000269|PubMed:12403813, ECO:0000269|PubMed:12496130, ECO:0000269|PubMed:12730220, ECO:0000269|PubMed:7828598, ECO:0000269|PubMed:8682855, ECO:0000269|PubMed:9017593}.</Function>
<Interactions>
<Interaction>
<Partner>P14907</Partner>
<IntAct>EBI-789044</IntAct>
<Score>0.35</Score>
</Interaction>
<Interaction>
<Partner>P32499</Partner>
<IntAct>EBI-6322501</IntAct>
<Score>0.00</Score>
</Interaction>
<Interaction>
<Partner>P32500</Partner>
<IntAct>EBI-6322567</IntAct>
<Score>0.00</Score>
</Interaction>
<Interaction>
<Partner>Q03790</Partner>
<IntAct>EBI-390816</IntAct>
<Score>0.67</Score>
</Interaction>
<Interaction>
<Partner>P53271</Partner>
<IntAct>EBI-390819</IntAct>
<Score>0.37</Score>
</Interaction>
<Interaction>
<Partner>P38305</Partner>
<IntAct>EBI-761900</IntAct>
<Score>0.40</Score>
</Interaction>
<Interaction>
<Partner>Q12315</Partner>
<IntAct>EBI-849734</IntAct>
<Score>0.32</Score>
</Interaction>
<Interaction>
<Partner>P07259</Partner>
<IntAct>EBI-789044</IntAct>
<Score>0.35</Score>
</Interaction>
<Interaction>
<Partner>P10592</Partner>
<IntAct>EBI-789044</IntAct>
<Score>0.35</Score>
</Interaction>
<Interaction>
<Partner>P48837</Partner>
<IntAct>EBI-789044</IntAct>
<Score>0.84</Score>
</Interaction>
<Interaction>
<Partner>Q02199</Partner>
<IntAct>EBI-789044</IntAct>
<Score>0.62</Score>
</Interaction>
<Interaction>
<Partner>P47054</Partner>
<IntAct>EBI-789044</IntAct>
<Score>0.55</Score>
</Interaction>
<Interaction>
<Partner>P40069</Partner>
<IntAct>EBI-789044</IntAct>
<Score>0.35</Score>
</Interaction>
<Interaction>
<Partner>P53863</Partner>
<IntAct>EBI-797840</IntAct>
<Score>0.35</Score>
</Interaction>
<Interaction>
<Partner>P40066</Partner>
<IntAct>EBI-813993</IntAct>
<Score>0.27</Score>
</Interaction>
<Interaction>
<Partner>Q07953</Partner>
<IntAct>EBI-857992</IntAct>
<Score>0.00</Score>
</Interaction>
<Interaction>
<Partner>Q02630</Partner>
<IntAct>EBI-1269736</IntAct>
<Score>0.00</Score>
</Interaction>
<Interaction>
<Partner>Q02629</Partner>
<IntAct>EBI-1269879</IntAct>
<Score>0.00</Score>
</Interaction>
<Interaction>
<Partner>P51998</Partner>
<IntAct>EBI-2347558</IntAct>
<Score>0.37</Score>
</Interaction>
<Interaction>
<Partner>P23291</Partner>
<IntAct>EBI-2614250</IntAct>
<Score>0.35</Score>
</Interaction>
<Interaction>
<Partner>P26448</Partner>
<IntAct>EBI-2882390</IntAct>
<Score>0.00</Score>
</Interaction>
<Interaction>
<Partner>Q00684</Partner>
<IntAct>EBI-2882792</IntAct>
<Score>0.00</Score>
</Interaction>
<Interaction>
<Partner>P22696</Partner>
<IntAct>EBI-2883245</IntAct>
<Score>0.00</Score>
</Interaction>
<Interaction>
<Partner>P02293</Partner>
<IntAct>EBI-2884858</IntAct>
<Score>0.00</Score>
</Interaction>
<Interaction>
<Partner>P38265</Partner>
<IntAct>EBI-2885494</IntAct>
<Score>0.00</Score>
</Interaction>
<Interaction>
<Partner>P39723</Partner>
<IntAct>EBI-2887969</IntAct>
<Score>0.00</Score>
</Interaction>
<Interaction>
<Partner>Q04477</Partner>
<IntAct>EBI-2887856</IntAct>
<Score>0.00</Score>
</Interaction>
<Interaction>
<Partner>P46675</Partner>
<IntAct>EBI-2888241</IntAct>
<Score>0.00</Score>
</Interaction>
<Interaction>
<Partner>P52593</Partner>
<IntAct>EBI-4324997</IntAct>
<Score>0.37</Score>
</Interaction>
<Interaction>
<Partner>P52919</Partner>
<IntAct>EBI-7042849</IntAct>
<Score>0.27</Score>
</Interaction>
<Interaction>
<Partner>Q7Z3B4</Partner>
<IntAct>EBI-11889076</IntAct>
<Score>0.37</Score>
</Interaction>
<Interaction>
<Partner>Q05166</Partner>
<IntAct>EBI-11889154</IntAct>
<Score>0.37</Score>
</Interaction>
</Interactions>
<OntologyTerms>
<Ontology>GO:0005635</Ontology>
<Ontology>GO:0031965</Ontology>
<Ontology>GO:0005643</Ontology>
<Ontology>GO:0044612</Ontology>
<Ontology>GO:0044615</Ontology>
<Ontology>GO:0017056</Ontology>
<Ontology>GO:0006999</Ontology>
<Ontology>GO:0006913</Ontology>
<Ontology>GO:0016973</Ontology>
<Ontology>GO:0006606</Ontology>
<Ontology>GO:0000055</Ontology>
</OntologyTerms>
<Topology>
        <Type>Peripheral</Type>
        <Source>UniProt</Source>
        <Annotation>Sequence Analysis</Annotation>
        </Topology>
<Sequence>MLETLRGNKLHSGTSKGANKKLNELLESSDNLPSASSELGSIQVSINELRRRVFQLRSKNKASKDYTKAHYLLANSGLSFEDVDAFIKDLQTNQFLEPNPPKIIESEELEFYIRTKKEENILMSIEQLLNGATKDFDNFINHNLNLDWAQHKNEVMKNFGILIQDKKTVDHKKSISSLDPKLPSWGNKGNNILNSNESRLNVNENNILREKFENYARIVFQFNNSRQANGNFDIANEFISILSSANGTRNAQLLESWKILESMKSKDINIVEVGKQYLEQQFLQYTDNLYKKNMNEGLATNVNKIKSFIDTKLKKADKSWKISNLTVINGVPIWALIFYLLRAGLIKEALQVLVENKANIKKVEQSFLTYFKAYASSKDHGLPVEYSTKLHTEYNQHIKSSLDGDPYRLAVYKLIGRCDLSRKNIPAVTLSIEDWLWMHLMLIKEKDAENDPVYERYSLEDFQNIIISYGPSRFSNYYLQTLLLSGLYGLAIDYTYTFSEMDAVHLAIGLASLKLFKIDSSTRLTKKPKRDIRFANILANYTKSFRYSDPRVAVEYLVLITLNEGPTDVELCHEALRELVLETKEFTVLLGKIGRDGARIPGVIEERQPLLHVRDEKEFLHTITEQAARRADEDGRIYDSILLYQLAEEYDIVITLVNSLLSDTLSASDLDQPLVGPDDNSETNPVLLARRMASIYFDNAGISRQIHVKNKEICMLLLNISSIRELYFNKQWQETLSQMELLDLLPFSDELSARKKAQDFSNLDDNIVKNIPNLLIITLSCISNMIHILNESKYQSSTKGQQIDSLKNVARQCMIYAGMIQYRMPRETYSTLINIDVSL</Sequence>
        <SequenceLength>839</SequenceLength>
        </Entry>