<Entry>
<Accession>P40532</Accession>
        <ProteinName>Nuclear</ProteinName>
        <GeneName>APQ12</GeneName>
        <OS_id>559292</OS_id>
        <ReferenceProteome>None</ReferenceProteome>
        <SubcellularLocation>
<Location>SL-0178</Location>
<Location>SL-0182</Location>
<Comments>Nucleus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.</Comments>
</SubcellularLocation>
<CrossReferences>
<CrossReference>
<Database>UNIPROT</Database>
<ID>P40532</ID>
</CrossReference>
<CrossReference>
<Database>UNIPROT</Database>
<ID>D6VVP2</ID>
</CrossReference>
<CrossReference>
<Database>Pfam</Database>
<ID>PF12716</ID>
</CrossReference>
</CrossReferences>
<Function>Involved in the regulation of lipid homeostasis in the endoplasmic reticulum, thereby impacting nuclear pore complex biogenesis and localization, and nucleocytoplasmic mRNA transport. {ECO:0000269|PubMed:15273328, ECO:0000269|PubMed:17724120, ECO:0000269|PubMed:20016074}.</Function>
<Interactions>
<Interaction>
<Partner>P11484</Partner>
<IntAct>EBI-3685195</IntAct>
<Score>0.35</Score>
</Interaction>
<Interaction>
<Partner>P32589</Partner>
<IntAct>EBI-3723382</IntAct>
<Score>0.35</Score>
</Interaction>
</Interactions>
<OntologyTerms>
<Ontology>GO:0005783</Ontology>
<Ontology>GO:0005789</Ontology>
<Ontology>GO:0016021</Ontology>
<Ontology>GO:0005635</Ontology>
<Ontology>GO:0031965</Ontology>
<Ontology>GO:0055088</Ontology>
<Ontology>GO:0051028</Ontology>
<Ontology>GO:0006998</Ontology>
</OntologyTerms>
<Topology>
        <Type>Transmembrane</Type>
        <Source>UniProt</Source>
        <Annotation>Sequence Analysis {ECO:0000255}</Annotation>
        </Topology>
<Sequence>MDATQPQYELSVVTQCLKSAIDVIQWLIPTITKFSQSHPLVFQLLFIFFTFYVFYKLLMNFITLVKRFLYLTLVVTCIGIYMRGSQQFLTVDLLNFYNFVMSNRYYAFKIYTLFINALEREINTVYHLAQMKMEQLLK</Sequence>
        <SequenceLength>138</SequenceLength>
        </Entry>