P46062 Signal-induced Sipa1 10090 None SL-0198 Nucleus {ECO:0000269|PubMed:7799964}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q96FS4}. Endomembrane system; Peripheral membrane protein {ECO:0000250|UniProtKB:Q96FS4}. Note=Mostly localized in the perinuclear membraneous region. {ECO:0000250|UniProtKB:Q96FS4}. UNIPROT P46062 UNIPROT P70204 Pfam PF00595 Pfam PF02145 PROSITE PS50106 PROSITE PS50085 GTPase activator for the nuclear Ras-related regulatory proteins Rap1, Rsr1 and Ran in vitro, converting them to the putatively inactive GDP-bound state. Affects cell cycle progression. {ECO:0000269|PubMed:7799964}. Q4U2R1 EBI-16730475 0.35 Q7TPH6 EBI-16731507 0.35 GO:0005737 GO:0016020 GO:0005634 GO:0048471 GO:0032991 GO:0030133 GO:0005096 GO:0008022 GO:0090630 GO:0042631 GO:0051726 GO:0051056 Peripheral UniProt By Similarity {ECO:0000250|UniProtKB:Q96FS4} MWAGGVGSPRRGMAPAPTDDLFARKLRQPARPPLTPNTFEPRPARGPLLRSGSDAGEVRPPTPASPRARAHSHEDASRPAATPTRLFTDPLALLGLPAEEPEPTFPPVLEPRWFAHYDVQSLLFDWAPRPRGTGSHTEANSGTLAEGQTTTSDLLLGAPGFVSELGGEGELGLGGPISPPVPPALPNAAVSVLEEPQTRTTTYSLEHADLGAGYYRKYFYGKEHQNFFGLDEALGPVAVSLRREEKEGSGGGTLHSYRVIVRTTQLRTLRGTISEDALPPGPPSVSPRKLLEHVAPRLSPTCLRLGSASPKVPRQLLTLDEQVLSFQRKGGILYCRAGQGSEEEMYNNQEAGAAFMQFLTLLGDVVRLKGFESYRAQLDTKTDSTGTHSLYTTYQDHEIMFHVSTMLPYTPNNQQQLLRKRHIGNDIVTIVFQEPGSKPFCPTTIRSHFQHVFLVVRAHAPCTPHTSYRVAVSRTQDTPAFGPALPEGGGPFAANADFRAFLLAKALNGEQAAGHARQFHAMATRTRQQYLQDLATNEVTTTSLDSASRFGLPSLGGRRRATPRSPGADVQAAGALMWGVRAAPGARVAAGAETSGPDDAEVPCLLGISAETLVLVAPRDGRVVFNCACRDVLAWTFSEHQLDLYHGRGEAITLRLDGAPGQAVGEVVARLQLVSRGCETRELALPRDGQGRLGFEVDAEGFITHVERFTFAETTGLRPGARLLRVCGQTLPKLGPETAAQMLRSAPKVCVTVLPPDESGRPRRSFSELYMLSLKEPSRRGGPEPVQDETGKLVILPPTKQLLHFCLKDSSSPPGPGDLTEERTEFLRTHNSLSSGSSLSDEAPVLPNTTPDLLLVTTANPSAPGTDRETPPSQDQSGSPSSHEDTSDSGPELRASILPRTLSLRNSISKIMSEAGSETLEDEWQSISEIASTCNTILESLSREGQPISESGDPKEALKCDSEPEPGSLSEKVSHLESMLWKLQEDLQREKADRAALEEEVRSLRHNNQRLLAESESAATRLLLASKHLGAPTTDLA 1037