P52591 Nuclear Pom121 10116 None SL-0178 SL-0182 SL-0185 Nucleus, nuclear pore complex {ECO:0000269|PubMed:11448991}. Nucleus membrane {ECO:0000269|PubMed:11448991}; Single-pass membrane protein {ECO:0000269|PubMed:11448991}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:11448991}; Single-pass membrane protein {ECO:0000269|PubMed:11448991}. Note=Stably associated with the NPC throughout interphase and the endoplasmic reticulum during metaphase. UNIPROT P52591 PDB 4YI0 Essential component of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane. When overexpressed in cells induces the formation of cytoplasmic annulate lamellae (AL). GO:0005789 GO:0016021 GO:0005635 GO:0031965 GO:0005643 GO:0008139 GO:0017056 GO:0051028 GO:0006999 GO:0006606 GO:0006405 Transmembrane UniProt Sequence Analysis {ECO:0000255} MSPAAAAADGGERRRPPLGVREGRGRTRGCGGPAGAAALGLALLGLALYLVPAAAALAWLAVGASAAWWGLSREPRGPRGLSSFVRESRRHPRPALTASPLPAKSPVNGSLCEPRSPLGGPDPAELLLMGSYLGKPGPPEPALPQDPRDRPGRRPPSRSPPSSSTAQRVHHVYPALPTPLLRPSRRPPHRDCGPLSSRFVITPRRRYPIQQAQYSLLGALPTVCWNGGHKKAVLSARNSRMVCSPVTVRIAPPDSKLFRSPMPEQILSTTLSSPSSNAPDPCAKETVLNALKEKKKRTVAEEDQLHLDGQENKRRRHDSSGSGHSAFEPLVANGVPAAFVPKPGSLKRSLASQSSDDHLNKRSRTSSVSSLTSTCTGGIPSSSRNAITSSYSSTRGVSQLWKRSGPTSSPFSSPASSRSQTPERPAKKTREEEPCHQSSSSAPLVTDKESPGEKVTDPATGKQQSLWTSPPTPGSSGQRKRKIQLLPSRRGDQLTLPPPPELGYSITAEDLDMERRASLQWFNKVLEDKTDDASTPATDTSPATSPPFTLTLPTVGPAASPASLPAPSSNPLLESLKKMQESPAPSSSEPPEAATVAAPSPPKTPSLLAPLVSPLTGPLASTSSDSKPTTTFLGLASASSATPLTDTKAPGVSQAQLCVSTPAATAPSPTPASTLFGMLSPPASSSSLATPGPACASPMFKPIFPATPKSESDNPLPTSSSAATTTPASTALPTTATATAHTFKPIFESVEPFAAMPLSPPFSLKQTTAPATTAATSAPLLTGLGTATSTVATGTTASASKPVFGFGVTTAASTASTIASTSQSILFGGAPPVTASSSAPALASIFQFGKPLAPAASVAGTSFSQSLASSAQTAASNSSGGFSGFGGTLTTSTSAPATTSQPTLTFSNTVTPTFNIPFSASAKPALPTYPGANSQPTFGATDGATKPALAPSFGSSFTFGNSVASAPSAAPAPAAFGGAAQPAFGGLKASASTFGTPASTQPAFGSTTSVFSFGSATTSGFGAAAATTQTTHSGSSSSLFGSSTPSPFTFGGSAAPAGGGGFGLSATPGTGSTSGTFSFGSGQSGTTGTTTSFGGSLSQNTLGAPSQSSPFAFSVGSTPESKPVFGGTSTPTFGQSAPAPGVGTTGSSLSFGAPSTPAQGFVGVGPFGSGAPSFSIGAGSKTPGARQRLQARRQHTRKK 1199