<Entry>
<Accession>Q14542</Accession>
        <ProteinName>Equilibrative</ProteinName>
        <GeneName>SLC29A2</GeneName>
        <OS_id>9606</OS_id>
        <ReferenceProteome>None</ReferenceProteome>
        <SubcellularLocation>
<Location>SL-0178</Location>
<Location>SL-0182</Location>
<Comments>Basolateral cell membrane {ECO:0000269|PubMed:12527552}; Multi-pass membrane protein {ECO:0000269|PubMed:12527552}. Nucleus membrane {ECO:0000269|PubMed:12527552}; Multi-pass membrane protein {ECO:0000269|PubMed:12527552}. Note=Localized at the basolateral cell membrane in polarized MDCK cells.</Comments>
</SubcellularLocation>
<CrossReferences>
<CrossReference>
<Database>UNIPROT</Database>
<ID>Q14542</ID>
</CrossReference>
<CrossReference>
<Database>UNIPROT</Database>
<ID>B3KPY7</ID>
</CrossReference>
<CrossReference>
<Database>UNIPROT</Database>
<ID>O43530</ID>
</CrossReference>
<CrossReference>
<Database>UNIPROT</Database>
<ID>Q52M84</ID>
</CrossReference>
<CrossReference>
<Database>UNIPROT</Database>
<ID>Q96R00</ID>
</CrossReference>
<CrossReference>
<Database>UNIPROT</Database>
<ID>Q9UPE0</ID>
</CrossReference>
<CrossReference>
<Database>Pfam</Database>
<ID>PF01733</ID>
</CrossReference>
<CrossReference>
<Database>OMIM</Database>
<ID>602110</ID>
</CrossReference>
<CrossReference>
<Database>DisGeNET</Database>
<ID>3177</ID>
</CrossReference>
</CrossReferences>
<Function>Mediates equilibrative transport of purine, pyrimidine nucleosides and the purine base hypoxanthine. Very less sensitive than SLC29A1 to inhibition by nitrobenzylthioinosine (NBMPR), dipyridamole, dilazep and draflazine. {ECO:0000269|PubMed:9396714}.</Function>
<Interactions>
<Interaction>
<Partner>O43889</Partner>
<IntAct>EBI-8649617</IntAct>
<Score>0.37</Score>
</Interaction>
<Interaction>
<Partner>P60033</Partner>
<IntAct>EBI-25645944</IntAct>
<Score>0.35</Score>
</Interaction>
</Interactions>
<OntologyTerms>
<Ontology>GO:0016323</Ontology>
<Ontology>GO:0005887</Ontology>
<Ontology>GO:0031965</Ontology>
<Ontology>GO:0005730</Ontology>
<Ontology>GO:0005886</Ontology>
<Ontology>GO:0098793</Ontology>
<Ontology>GO:0005326</Ontology>
<Ontology>GO:0005337</Ontology>
<Ontology>GO:0015211</Ontology>
<Ontology>GO:0015213</Ontology>
<Ontology>GO:0015853</Ontology>
<Ontology>GO:0032238</Ontology>
<Ontology>GO:0032869</Ontology>
<Ontology>GO:0015854</Ontology>
<Ontology>GO:0035344</Ontology>
<Ontology>GO:0007595</Ontology>
<Ontology>GO:0098810</Ontology>
<Ontology>GO:0006836</Ontology>
<Ontology>GO:0001504</Ontology>
<Ontology>GO:1901642</Ontology>
<Ontology>GO:0015858</Ontology>
<Ontology>GO:0015860</Ontology>
<Ontology>GO:0072531</Ontology>
<Ontology>GO:0035364</Ontology>
<Ontology>GO:0150104</Ontology>
<Ontology>GO:0015862</Ontology>
<Ontology>GO:0006855</Ontology>
</OntologyTerms>
<Topology>
        <Type>Transmembrane</Type>
        <Source>UniProt</Source>
        <Annotation>Sequence Analysis {ECO:0000255}</Annotation>
        </Topology>
<Sequence>MARGDAPRDSYHLVGISFFILGLGTLLPWNFFITAIPYFQARLAGAGNSTARILSTNHTGPEDAFNFNNWVTLLSQLPLLLFTLLNSFLYQCVPETVRILGSLLAILLLFALTAALVKVDMSPGPFFSITMASVCFINSFSAVLQGSLFGQLGTMPSTYSTLFLSGQGLAGIFAALAMLLSMASGVDAETSALGYFITPCVGILMSIVCYLSLPHLKFARYYLANKSSQAQAQELETKAELLQSDENGIPSSPQKVALTLDLDLEKEPESEPDEPQKPGKPSVFTVFQKIWLTALCLVLVFTVTLSVFPAITAMVTSSTSPGKWSQFFNPICCFLLFNIMDWLGRSLTSYFLWPDEDSRLLPLLVCLRFLFVPLFMLCHVPQRSRLPILFPQDAYFITFMLLFAVSNGYLVSLTMCLAPRQVLPHEREVAGALMTFFLALGLSCGASLSFLFKALL</Sequence>
        <SequenceLength>456</SequenceLength>
        </Entry>