Q6CLY1 Nuclear NPL4 284590 None SL-0178 SL-0182 SL-0198 Cytoplasm, perinuclear region {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Nucleus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Localizes mainly at the nuclear periphery and the endoplasmic reticulum membrane. {ECO:0000250}. UNIPROT Q6CLY1 Pfam PF05021 Pfam PF11543 Pfam PF05020 PROSITE PS50249 Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity). {ECO:0000250}. GO:0036266 GO:0000837 GO:0000839 GO:0031965 GO:0048471 GO:0030894 GO:1990112 GO:0034098 GO:0071629 GO:0006274 GO:0071712 GO:0072671 GO:0051228 GO:0051028 GO:0051974 GO:0070651 GO:1900182 GO:0072665 GO:0030970 GO:1990116 GO:0030433 Peripheral UniProt By Similarity {ECO:0000250} MLLRLRSKLGIHRVSCEGNDNFGSVIEKWANQLRLNVDPDSVSVSTQPGVSKLMTEIAHQGVESLGLRHGDMVTVEFKVLDTEEKNVSEKEMTNMTVSASTTSVPISSSHNKGSIRGKVKESALDIELEGETGLIPRSRSSLCRHGEKGMCEYCSPLPPWDKGYQDEHSIKHISFHAYLKQLDEVTNKKSSGSSYIPPLSEPNYEINLNCAGGHEPWPKGICSKCQPSAITLQQQSFRMVDHVEFQESELINQFIDSWRTTGMQRFGYLYGYYKRYDNVPLGIKAVVEAIWEPPQHDEQDGLTMDMDQVVKEVEDTDKLAREMGLERIGMIFTDLTDTGLGDGSVYCKRHKDSFFLSSLEVIMAAKHQLRHPNVSKFSETGLFSSRFVTCCISGNLNQEIDIATYQVSIEAEGLVEADLISGSTHPSQAYINETNDKRYVPEIFYTRKNEYNLTVKQNAKPAFPVDYLLVSLTHGFPKETDDDSTTTANTTTVFKTVAGFPWTNRQAMGQSQDYTELKRYVYKACTGNDLAELQAKLSNFHFLLYLHSIEVLNQQEWSLLIRTVTAPTLHEATEPLLNLINSPGWQTFVMILEQSM 596